本論文主要是探討利用導電奈米鑽石當作工作電極，再利用氧化銅、氫氧化鎳做修飾，最後再利用不同結構的基板來製作葡萄糖感測器，探討從結構及材料種類及材料厚度來實驗出最佳的葡萄糖感測器條件，本論文利用MPCVD沉積摻雜氮的導電奈米鑽石薄膜當做工作電極，利用濺鍍設備濺鍍金屬鎳及氧化銅，再利用循環伏安法使金屬鎳改質成氫氧化鎳，最後進行元件的物性及葡萄糖靈敏度量測，其結果為有加金字塔結構的靈敏度相對較高，在氫氧化鎳部分，氫氧化鎳(100nm)厚度濺鍍於金字塔結構鑽石薄膜的靈敏度有最高的值3070(μA mM −1 cm −2)，而在氧化銅的部分，氧化銅(75nm)厚度濺鍍於金字塔結構鑽石薄膜的靈敏度有最高的值1993(μA mM −1 cm −2)，而就穩定性分析來說，氧化銅的試片平均在元件放置28天後只衰減不到其靈敏度的10%，但氫氧化鎳的試片平均在元件放置28天後衰減其靈敏度的36%，可見氧化銅比氫氧化鎳有更好的穩定性，其中導電鑽石薄膜提供良好的葡萄糖傳感特性，對於未來生物感測之應用具有一定的潛力。

We have designed glucose sensors based on the use of highly conducting nitrogen incorporated diamond film (NDFs) electrodes grown by microwave plasma enhanced chemical vapor deposition. The post deposition of Ni(OH)2 and CuO on Pyramidal NDFs and plane NDFs, which reveal differences for the glucose detection. The systematic cyclic voltammetry measurements on the 100nm thickness of Ni(OH)2 on the pyramidal NDFs glucose sensors attains higher sensitivity properties(3070(μA mM-1 cm-2)) than those of Ni(OH)2(120nm)/plane NDFs(2444(μA mM-1 cm-2)) and CuO(75nm)/pyramid NDFs glucose sensors(1993(μA mM-1 cm-2)).
In terms of stability, CuO/NDFs based sensors reveals much better stability than Ni(OH)2/NDFs based sensors. The CuO/NDFs test chips were decreased less than 10% however, Ni(OH)2/NDFs based sensors were decreased up to 36% after exposing in air at room temperature for 28 days.
The higher sensitivity with high selectivity and reliable stability might be due to the use of the highly electrically conductive diamond film electrodes, which is responsible for good glucose sensing properties, and exhibits a significant degree of potential on the future bio-sensing applications.

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