本研究論文合成並研究三種具兒茶酚官能基之聚合物，CCDP-PVP(CP), DHCA-PLL-PVP(DPP), DHCA-PLL-PVP-CCDP(DPPC)。ε-聚賴氨酸以碳二亞胺類與羥基琥珀醯亞胺為偶聯劑與二氫咖啡酸和羧酸化聚乙烯吡咯烷酮進行醯胺化反應合成PLL-g-DHCA-g-PVP(DPP)，利用聚乙烯吡咯烷酮上三級胺與含氯兒茶酚單體(CCDP)進行SN2反應合成CP,再以DPP與CCDP以SN2反應合成PLL-g-DHCA-g-PVP-g-CCDP(DPPC)。藉由IR, 1H-NMR, GPC鑑定合成結果，實驗表明IR 在1462 cm-1 有吸收峰表明四級銨鹽之碳氮鍵(C-N)伸縮震動(stretching)存在。由1H-NMR可觀測到聚合物DPPC有數個苯環之氫的化學位移，GPC結果亦顯示分子量增加，可推估為SN2反應可發生於聚合物DPP上導致。由BCA蛋白濃度法定量於高分子上兒茶酚胺濃度，並將聚合物各自塗佈於玻璃、PET膜與孔洞PP薄膜。
應用性研究中，藉由接觸角測試得知DPPC塗佈之玻璃及PP薄膜接觸角分別為11.3°及36.2°，證實DPPC使表面更加具有親水性。抗汙測試中，BCA蛋白濃度法定量吸附於PP薄膜上的牛血清(BSA)蛋白吸附量，結果卻表明DPPC含有1126.51 μg/cm2 之蛋白吸附，推測是DPPC含有高於30% 之兒茶酚含量導致，氧化兒茶醌不利於表面塗佈，兒茶酚胺干擾BCA蛋白濃度法。過氧化氫經實驗表明可與表面的聚乙烯吡咯烷酮之雜環形成錯合物並經乙醇及清水潤洗後殘留，使過錳酸鉀還原退色。在抑菌圈測試中，DPPC具有明顯的抑制大腸桿菌生長(E.coli)菌圈。其亦有與碘錯合，抑菌效果優於碘酒精溶液。

Catechol-branched polymers have been utilized in various synthetic routes. One of the purposes is to utilize adhesion ability for coating on different substrates. Poly(vinyl-pyrrolidone) is an excellent polymer applied to antifouling due to its hydrophilicity.
The aim of the research is to synthesize a catechol functionalized ε-polylysine with poly(vinyl-pyrrolidone) pendant based on thiol-ene reaction and carbodiimide/N-hydroxysuccinimide activated coupling and get DPP. In addition, we coupled the catechol group by quaternary amine bond on the pyrrolidone ring to produce a multi-catechol polymer, DPPC, characterized by FT-IR, GPC, 1H-NMR. To investigate its antifouling and antimicrobial ability, we performed the contact angle test, and protein resistance test by BCA assay, and then applied the DPPC for substrate coating, such as glass, PET, PP membrane.
The result showed that DPPC endowed substrates with hydrophilicity since the contact angle decreased to 11.3° and 36.2° respectively on glass and PP membranes. BCA assay indicated that DPPC coated pp membrane with high content of protein adsorbed (1126.51 μg/cm2). It can be referred that DPPC is not favorable on the substrate due to catechol content higher than 30%, prone to oxidized quinone formation. Hydrogen peroxide and iodine is proved to remain on the substrate which form complex by pyrrolidone pendant. In the inhibition test, E.coli was observed restrained by iodine released from povidone iodine complex in DPPC sample which is better than iodine ethanol solution.

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