膽管支架(Biliary Stent)為一種中空管狀結構的醫療器材，在近幾年則被廣泛應用在因惡性腫瘤造成之阻塞性黃疸姑息治療，其中自我擴張式金屬支架(Self-expandable Biliary Stent)材料中最常見材料為鎳鈦合金。
在此篇論文研究中以超短脈衝雷射(350 fs)及反射式掃描振鏡進行鎳鈦管材上的膽管支架結構加工，其外部直徑為5.116 mm、厚度0.234 mm以及管長100 mm。鎳鈦曲面加工從量測焦距位置、雷射切割參數優化測試，進行膽管支架切割，達到高切邊品質且無熱效應區產生之膽管支架。再精確的利用雷射光束的高斯分布進行膽管支架邊緣圓角化的以及同時進行傳統支架電解拋光兩種不同方式進行圓角化加工，避免支架邊緣直角處對於醫療上的非預期性的傷害。自實驗結果中顯示藉由雷射切割路徑修正可以大幅提升雷射切割效率，使材料切割深度移除率從12 μm/J提升到27 μm/J，大幅減低熱能量累積於材料之中造成熱影響區。並且成功以飛秒雷射進行鎳鈦膽管支架邊緣之圓角化加工，去除其原始尖銳邊緣達到與電解拋光之相同效果。

Biliary stents has been extensively used an efficient medical device of palliation of jaundice for patients with biliary obstruction for many years. In addition, the most common material used for biliary stents was nickel-titanium (NiTi, Nitinol) alloy, also known as nitinol biliary stent, since NiTi alloy possessed some attracting materials properties.
In this study, an ultrashort pulse laser (350fs) and a galvano-mirror scanner were used to all experiments. Experiments are including nitinol biliary stent fabrication process, focal position measurement, and laser parameters optimization. The diameter of biliary stent was 5.116 mm, its thickness was 0.234 mm, and its length was 100 mm. In addition, the results indicated that the laser removal efficiency was significantly enhanced from 12 μm/J to 27 μm/J with high cutting quality without heat-affected zone producing if the laser movement path was precisely programmed. Moreover, compared laser machining rounded-shaped nitinol biliary stent with electropolished nitinol biliary stent, the edges of nitinol biliary stent can be successfully rounded-shaped without any side-effect by clever utilizing the unique characteristic of Gaussian beam of laser on the edges of biliary stent.

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