近幾年生物醫學科技的發展蓬勃，非侵入式成像技術的進步對於醫療診斷及後續治療給予了不小的貢獻。掃頻式光學同調斷層掃描（Swept-Source Optical coherence tomography, SS-OCT）具有小範圍但高解析度、非接觸及非侵入式即時成像的特點，因此在近年來成為眼科、牙科等醫學檢測的利器，讓醫師能更加了解病變位置的情況，助於後續的診斷和治療。為降低掃頻雷射輸出所產生的非線性現象對SS-OCT在計算空間距離時所產生的誤差，因此在系統中加入輔助干涉儀(Auxiliary Interferometer)進行量測修正。由於光纖型輔助干涉儀所需的體積龐大，因此本論文藉由絕緣層上覆矽（Silicon-on-insulator, SOI）技術結合輔助干涉儀系統來達到晶片化，以解決體積過大之問題。
本論文將針對掃頻雷射的非線性現象對SS-OCT系統量測結果之影響作探討。首先架設光纖型SS-OCT系統量測其縱向解析度、橫向解析度與靈敏度，之後，再結合光纖型輔助干涉儀系統，利用跨零點（zero crossing）的方式進行訊號處理，並進行比對，觀測後驗證使用輔助干涉儀有益於解決掃頻雷射非線性現象在SS-OCT系統上所產生之誤差。透過上述論證，再將輔助干涉儀系統的概念晶片化以縮小系統體積，並進行量測驗證，證實與光纖型輔助干涉儀系統有相同之功效。
實驗結果顯示掃頻雷射的非線性現象對於SS-OCT系統有明顯影響，未使用輔助干涉儀系統所量測解析度明顯比使用輔助干涉儀時低於許多，而使用晶片型輔助干涉儀則跟光纖型輔助干涉儀的量測結果相似，說明輔助干涉儀設計在晶片上不僅解決體積過大的問題亦可達到與光纖型相同的量測結果。

In recent years, biomedical technology development has been booming, and the advancement of non-invasive imaging technology has significantly contributed to medical diagnosis and follow-up treatment. Swept-Source Optical coherence tomography (SS-OCT) has the characteristics of a small area but high resolution, non-contact and non-invasive real-time imaging. Therefore, it has become a powerful tool for medical testing in ophthalmology and dentistry in recent years, allowing physicians to understand the condition of lesion locations better and facilitating follow-up diagnosis and treatment. For the SS-OCT error reduction in calculating the spatial distance due to the nonlinear modulation of the output laser, an auxiliary interferometer (AI) is implemented for characterization correction. Due to the large size of the fiber-optic AI, silicon-on-insulator (SOI) technology is utilized to demonstrate the chip-based AI in a small footprint.
In this thesis, the nonlinear phenomenon effect of the swept laser in the SS-OCT system is investigated by first setting up a fiber-based SS-OCT system to measure the longitudinal resolution, lateral resolution, and sensitivity. Then a fiber-based AI is implemented to compensate for the signal nonlinearity through the zero crossing method. The experimental data show that the AI helps correct the nonlinear errors generated by the nonlinear phenomenon of the frequency-swept laser in the SS-OCT system. Through the above demonstration, the concept of the AI system is formed as a silicon chip for size reduction. And its measurement shows the same effective performance as the fiber optic SI system.

The measurement results of the chip-typed AI are similar to those of the fiber-typed AI, which shows that the chip-based AI does not only solve the problem of large volume but also achieves the same measurement results as the fiber-typed AI.

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