生醫感測是目前世上不可或缺的重要技術，不只是生物體內的物質檢測與健康監測，外來的細菌與病，甚至是片段的DNA與RNA序列，都是生物感測技術活躍的範疇；當然感測技術不只活躍於微觀物質在量」捕捉，在生物組織方面，結合光的運用，捕捉「影像」，做到細微結構的觀察，也是生物感測的領域。而光學干涉就是其中一種廣泛運用於其中的基礎，光學干涉以光程差產生相位差，微小的相位變化，也能夠給予可觀的貢獻。
其中之一應用光學干涉的生醫技術為表面電漿共振(Surface Plasmon Resonance, SPR)技術，輸入特 定光波長和特定角度，以橫向磁場(TM)模光激發SPR，不同的待測物折射率，會造成TM模光的相位改，而橫向電場 (TE)模光則未和金屬產生 SPR效應，因此合併後的 TE與 TM模 將有光程差，形成干涉譜來辨識微量待測物質達成0.178的論解析度與9.256×10−5的實驗靈敏度。
在生醫影像辨識方面，將自製的P-I-N光偵測器(Photodetector, PD)運用於掃頻式光學同調斷層掃描術(Swept-Source Optical Coherence Tomography, SS-OCT)系統中，目標是完成SSOCT系統積體集成化。本論文著重研究於SS-OCT干涉端的光訊號接收，說明PD的運作原理以及商品化的製程步驟，完成達到響應度1以上的P-I-N PD元件再結合轉阻放大器 (Transimpedance Amplifier, TIA)，來做干涉訊號的接收與放大，並與業界的Balanced Photo-Detector(BPD)做比較。

Biomedical sensing is an essential and indispensable technology in the world, not only for material detection and health monitoring in living organisms but also for external bacteria and viruses and even for fragments of DNA and RNA sequences, which are all in the prevailing biosensing technologies. Besides the sensing technology capturing the "quantity" of microscopic substances, we can combine the use of light to form "images" for delicate structures observation, which is also a field of biological sensing. Optical interference is one of the widely used bases for biosensing technologies. Optical interference produces phase difference by optical path difference, and a small phase change can contribute considerably.
One of the biomedical techniques for optical interference is Surface Plasmon Resonance (SPR), where a specific wavelength and angle of light are input to excite SPR with the transverse magnetic field (TM) mode light under various analytes. However, the transverse electric (TE) mode has no plasmon effect. Therefore, the combined TE and TM modes will differ in the optical range, forming an interference spectrum to identify the analyte quantitatively.
In biomedical image recognition, a homemade P-I-N Photodetector (PD) is applied to the Swept-Source Optical Coherence Tomography (SS-OCT) system. This thesis focuses on the optical interferometric signal reception at the end of SS-OCT to demonstrate the operation principle of PD and the commercialization process steps. The Transimpedance Amplifier (TIA) is directly connected to PD for interferometric signal amplification. The commercial Balanced Photodetector (BPD) is utilized for the SS-OCT performance comparison.

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