膽管癌(Cholangiocarcinoma)為一種肝膽腫瘤，可能造成膽管阻塞並導致阻塞性黃疸。現今治療方式之一為膽管支架放置術，此方式為將支架利用細導管送至膽管阻塞部位後，使支架撐開阻塞的膽管，讓膽汁流通，提高癌症病患的存活時間及生活品質。
本研究利用脈衝光纖雷射切割膽管支架，首先找出最佳聚焦位置、雷射功率、脈衝重覆頻率及切割速度等參數進行測試，其最佳切割條件為雷射脈衝能量0.105mJ、脈衝重複頻率170kHz、切割速度1mm/s，並且使用乾燥空氣為輔助氣體，氣體壓力為0.6MPa進行支架雷射切割。切割完成之支架便進行擴張實驗，在實驗中發現支架結構在擴張時常有斷裂情形，初步判斷此問題與支架結構寬度不同有關，其發生原因可能為雷射加工精度不足所導致，造成支架結構擴張不均勻，部分結構應變過大，最終導致支架結構斷裂。在本篇論文中也進行了鎳鈦合金膽管支架雷射加工後的後處理製程實驗。在熱處理實驗中探討形狀記憶合金在不同熱處理時間其相轉變溫度(Af)之影響，此外也進行了鎳鈦合金膽管支架之酸洗與電解拋光實驗，並嘗試找出較佳的酸洗與電解拋光製程之操作參數。

Bile duct and gallbladder cancer may cause obstructive jaundice. One of current treatment methods is biliary stent placement technique. A biliary stent is delivered by a thin catheter to the site of obstruction, then the stent relieve the bile duct obstruction. Biliary stent placement technique can improve life quality and give longer survival time of cancer patients.
In this study, pulsed fiber laser was used to cut biliary stent. First, tests were performed to find the focus position, laser power, pulse repetition frequency and cutting speed and other operation parameters. The best cutting conditions for the laser are pulse energy 0.105mJ, pulse repetition frequency 170kHz, cutting speed 1mm/s, cutting one time with two offsets, and to use clean dry air with gas pressure 0.6MPa. The fabricated stents were used in the following expanding experiment. In the expanding experiment, the result indicated that the stent will devastate during the expanding process because the structure sizes of stent were not the same which was caused by laser fabrication inaccuracy. The different structure sizes formed an uniform stent expansion which causing the structure strain of stents was huge to devastate stents. In addition, in this study, the post treatment experiment of nitinol biliary stents was discussed, including heat treatment and electropolishing experiments. The heat treatment experiments showed the influence of NiTi phase transition temperature (Af) in different time. Furthermore, nitinol stents were also performed in successfully optimized electropolishing condition.

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