碳奈米廣泛的應用在生物這個領域。它們擁有高的表面積能讓他們結合分子實體。在這份研究當中，我們探討了新的奈米混合系統的合成以及結構特色的定量測定。作為基因遞送劑，已使用這些衍生物中的一種。 NH2 封端的聚 (酰胺胺) 樹枝狀聚合物優選用於修飾基因載體的CNH的表面官能基。
胺官能基的 CNH 與 DNA 和 PolyA 的生物材料發生靜電相互作用，因為胺官能化的 CNH 的表面電荷為正電荷，DNA 和 PolyA的生物材料帶負電荷，這兩種生物聚合物彼此靜電相互作用，表現為基因載體。在這項研究中，通過zeta電位、動態光散射和透射電子顯微鏡針對不同濃度的DNA和PolyA證實了帶有胺表面電荷的CNH攜帶DNA/PolyA。這項工作的進一步目的是使用 TGA 結果定量測定 DNA 和 PolyA 鏈數在一個 CNH 胺上的吸附量。這些結果使我們得出一個結論，這些奈米材料可以用作基因載體。

Carbon nanohorns provide a platform for a wide range of biological applications.
Their high surface area allows the incorporation of molecular entities. In this
work, we report the synthesis, structural characterization, and quantitative
determination of new hybrid systems of carbon nanohorns. As a gene delivery
agent, one of these derivatives has been used. The NH2-terminated poly (amide
amine) dendrimer is preferably used to modify surface functional groups of CNHs
for the gene carriers. The amine functionalized CNH is electrostatically interacting
with the biological material of DNA and PolyA, because the surface charge of
amine functionalized CNH is positive and the biological materials of DNA and
PolyA take a negative charge and these two biopolymers electrostatically interact
with each other, behaving as gene vector. In this study, the carrying of
DNA/PolyA by CNH with amine surface charge has been confirmed with zeta
potential, dynamic light scattering and transmission electron microscope for
different concentrations of DNA and PolyA. The further purpose of this work is
the quantitative determination of adsorption of DNA and PolyA chain number on
one CNH amine by using TGA results. These results allow us to conclude that
these nanomaterials can be exploited as useful for gene carrier.

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