人工髖關節的發展是手術發展中成功率較高的手術之一，針對現今臨床上全置換型髖關節設計的缺點，相關研究團隊開發了無柄髖關節，無柄髖關節的設計是只削除表面的壞死組織，保留大部分的原始髖關節，且不需掏空骨髓腔，利於二次手術的進行，還可改善術後產生應力遮蔽的情況，本研究將以實驗室自行研發設計的客制化無柄髖關節與目前臨床上使用的無柄髖關節，進行生物力學測試及有限元素分析，探討無柄髖關節植入物之幾何外型設計對股骨及植入物之應力的影響，以及了解無柄髖關節之骨釘方向對整體結構的影響。
本研究由電腦斷層掃描取得股骨剖面資料，再使用Amira 軟體建立股骨三維實體模型，另外以SolidWorks 軟體繪製相關客製化器械，再搭配3D列印技術製作成實體。將各式植入物植入股骨，施加重力負載於股骨頭，並固定股骨遠端，以模擬正常人步態站立期之情形與各種不同類型之植入物，進行生物力學測試及有限元素分析，從股骨von Mises應力及植入物最大主應力去探討植入物之幾何外型及其骨釘結構對股骨的影響，從本論文中可得到下列結論：臨床上使用的無柄髖關節其圓柱外型易造成鬆動，導致骨釘應力集中，骨釘發生斷裂的風險高，而客製化的無柄髖關節高貼合度的設計外型，穩固牢靠有較好的穩定性。
本研究結合醫學影像重建的技術，建構客製化髖關節之手術器械，依據規劃之手術流程加上實際打樣的成品，再經由生物力學測試及有限元素分析的結果證實，本實驗室開發之客製化無柄髖關節確實比臨床使用中之無柄關節效果好，期望本論文研究之結果對改進人工髖關節之設計參考有所幫助。

The replacements of artificial hip joints have shown the most significant progress among all artificial joint surgery. But from clinical observations, The total hip replacement still remain problems. The non-stemmed or resurfacing hip replacement were invented to overcome such problems.The non-stemmed system excises the bone quantities are few, can therefore retain the natural joint anatomy property as far as possible, On the other hand, the surgery will not change joints stress situation largely, causes the second surgery success ratio to enhance largely. This purpose of this study was to investigate the influences of the hip prosthesis designs on the load-transferring mechanism by biomechanical testing and finite element method. The results of the current study give further insight into the influences of the hip prosthesis on the proximal femur.
The geometry of the femur was three-dimensionally established from the computed tomography scanning images by Amira software. The solid models of the femur and the instrumented hip prostheses were created by SolidWorks software. The body load were applied on the femur, and the distal femur was fixed to simulate one-legged stance loading condition. For different shape designs of three kinds of implants, finite element analysis were performed using the SolidWorks Simulation. The objective of this study was to respectively discuss the influences of the implant designs on the femur using the von Mises stress criterion, and maximum principal stress of the implant. The results of this study suggested the following conclusions: the Custom-made implants was better than the cylinder implant because of decreasing the stress of the femur and implant ; among three types of implants, the parallel implant has the best of stability.
In this study, the combination of medical image reconstruction technique to construct customized hip of surgical instruments. According to planning of surgical procedures and proofing products. And then verify that the design of this thesis is really more effectual than the artificial joint prosthesis while using via the result of the biomechanical testing and finite element analysis. This study could assist the engineers to improve the design of artificial hip joints.

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