研究生: |
陳舒郁 Shu-Yu Chen |
---|---|
論文名稱: |
非侵入式腔室壓力量測於動物模型之研究 Animal model for The Study of Non-Invasive Compartment Pressure Measurement |
指導教授: |
張復瑜
Fuh-Yu Chang |
口試委員: |
張以全
I-Tsyuen Chang 陳階曉 Chieh-Hsiao Chen |
學位類別: |
碩士 Master |
系所名稱: |
工程學院 - 機械工程系 Department of Mechanical Engineering |
論文出版年: | 2016 |
畢業學年度: | 104 |
語文別: | 中文 |
論文頁數: | 109 |
中文關鍵詞: | 腔室症候群 、手機軟體應用程式 、有限元素法 |
外文關鍵詞: | compartment syndrome, mobile app, finite element method |
相關次數: | 點閱:216 下載:5 |
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腔室症候群發生的原因主要是因外傷骨折、壓砸傷、燒燙傷、動脈損傷與環狀石膏筒等情況引起。一旦發生可能須進行清創手術,更嚴重則將執行截肢甚至導致死亡。本研究主旨為設計一非侵入式壓力量測系統,以預防高風險患者發生腔室症候群之症狀。
本研究中,以IOS手機軟體應用程式來開發腔室壓力量測系統。受傷部位的各腔室壓力能透過非侵入式腔室壓力量測系統所量測,藉由結合所開發之App及置於受傷部位的撓性壓力感測器和所建立的有限元素分析模型。實驗選用與人體相似結構之豬隻前腿,以水注入豬腿腔室以達到腔室壓力上升狀況,透過撓性壓力感測器量取前腿外部的壓力,並經由專為豬前腿所建立之有限元素模型,以得知腔室壓力與感測器數值之間的關係。最後,比較實驗與模擬的結果並改善模擬模型。
動物模型之研究證實非侵入式壓力測量系統,可用於判斷患者的腔室壓力。這能幫助於醫生提前做預防性治療,以避免腔室症候群和相關併發症發生。
Compartment syndrome is mainly due to bone fracture, crushing injury, burns, arterial injury, annular gypsum cylinder…etc. Once it happens, debridement will be probably conducted and in the worst case, the patient will be amputated or even lead to death. To develop non-invasive compartment pressure measuring system for preventing patients who have a higher risk of compartment syndrome is the purpose of this study.
In this study, a dedicated IOS mobile app was developed for the compartment pressure measuring system. Combining the developed mobile app, flexible sensors arranged outside the injured area, and a developed finite element modelling, the compartment pressure in each compartment of injured area can be achieved by our non-invasive compartment pressure measuring system. Experiments were conducted on the pig foreleg, due to its similar structure to human leg. In our study water was injected into the compartments of pig foreleg to achieve the rising compartment pressure conditions. Then, the pressure distribution outside the foreleg was measured immediately by the flexible sensors. A finite element modelling dedicated to pig foreleg was also developed to know the relation between the compartment pressure and the measured pressure outside the leg. Finally, experiment and simulation results were compared in order to improve the developed simulation model.
The animal model study indicates our non-invasive compartment pressure measuring system is available to make reliable judgment of patient’s compartment pressure. It could be very helpful to allow physicians to do preventive treatment in advance to avoid compartment syndrome and related complications.
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