本研究針對生質柴油的副產物-甘油進行研究，探討甘油與叔丁醇醚化反應產生甘油第三丁基醚(GTBEs)，此醚類為汽油添加劑，可取代原先有毒的甲基第三丁基醚。
使用Aspen plus進行穩態模擬，熱力學模式與動力學參數取自於文獻。本研究利用反應蒸餾塔進行醚化製程，以最小年度總成本(TAC)為最適化之目標，得到最佳的操作條件。並利用Aspen dynamics 進行動態模擬，採用基本的控制環路控制，溫度控制則是針對溫度最敏感的板進行控制，觀察當干擾進入程序時的變化情形，藉由提出之架構能夠在進料低於±20 %時，得到良好的控制效果與維持產品的濃度，驗證此整廠程序操作之可行。

The study was research on byproduct of biodiesel -glycerol, glycerol and tert-butyl alcohol to explore etherification reactions to produce Glycerol Tertiary Butyl Ether (GTBEs), this ether as a gasoline additive, can be replaced original toxic methyl tertiary butyl ether.
Using Aspen plus to do steady-state simulation, thermodynamic and kinetic model parameters taken from the paper. In this etherification reaction use reactive distillation process, to the total annual cost (TAC) for the optimization of the minimum annual target, get the best operating conditions. Using aspen dynamics to do dynamic simulation, using the basic control loop , temperature control is to control the temperature of the stage for the most sensitive, to observe changes in the situation when the disturbance into the process, the overall process design can be lower than in the feed ± 20%, to obtain good control effect and maintain the concentration of the product, verify that the operation of the whole plant viable program.

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