腔室症候群(compartment syndrome, CS)發生的原因乃是組織內的壓力大過血液灌流的壓力，導致血液無法供應養分給組織。其可因各種傷害而產生，常見的原因包括長骨骨折、高能量的創傷、穿刺傷、靜脈損傷、壓碎性傷害……等，若壓力持續升高數小時，則會組織壞死而產生不可逆的損害。目前是利用探針直接插入所需量測之腔室中，測量腔室內的壓力值，來診斷是否有腔室症候群的危險。侵入式方法監測會遇到的問題是1.易傷及神經血管與後續可能的傷口感染2.需進入手術室才能使用。
因此，本研究應用撓性壓力感測器來開發一量測裝置，並於自行製作的小腿模型上進行量測實驗，再透過有限元素分析軟體ANSYS Workbench 14.5進行腔室壓力與撓性壓力感測器數值的模擬。另外，導入非線性材料的皮膚軟組織與肌肉的材料特性，模擬真實小腿發生腔室症候群時，小腿肌肉與感測器數值變化。最後，本研究將小腿模型實驗、模擬實驗以及真實小腿模擬實驗之結果，進行深入的分析與探討。

Compartment syndrome (CS) occurs when the tissue pressure within a closed muscle compartment exceeds the perfusion pressure and results in muscle and nerve ischemia. Common causes of compartment syndrome include long bone fractures, high-energy trauma, puncture wounds, venous injury, crush injuries. If the pressure continues to rise for several hours, then tissue will die and it may cause irreversible damage.
Currently, a needle is inserted into the area of suspected compartment syndrome while an attached pressure monitor records the pressure to diagnose the compartment syndrome. The invasive method has some problems: 1. neurovascular injuries and wound infections. 2. it has to be used in operaration room.
This study developed a non-invasive compartment pressure measuring system which is with flexble pressure sensors, and experiments were performed with this system on a lower leg CS simulation model. Compartment pressure and on skin pressure according to placed sensor positions were simulated by finite element analysis software ANSYS Workbench 14.5. In addition, the material properties of nonlinear materials, soft tissue and muscle, were applied in the theoretical simulation to approach the real lower leg compartment syndrome case, to study tissue and muscle deformation and pressure distribution. Finally, the results of the experiment and simulation were discussed in detail.

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