本研究以靜電紡絲製作PVDF薄膜，並探討其溶劑比例、溶液濃度、電場電壓和收集距離等參數，以製作最佳化ES PVDF膜。而後混入不同濃度之Pluronic F127，在最佳參數條件下製成ES PVDF-F127薄膜。使用SEM觀察薄膜表面型態，進一步以TGA和DSC分析膜的熱性質，凝血時間、蛋白質和血小板吸附作為血液相容的評估，最後以纖維母細胞L929進行細胞增生實驗測試。
由結果知ES PVDF-F127膜纖維直徑為205nm，孔徑大小為0.1μm，凝血時間並無異常，蛋白質和血小板吸附量大幅減少。在細胞增生方面纖維母細胞L929比之ES PVDF膜有明顯增加情形。

In this investigation, the PVDF electrospinning film was prepared using parameters including solvent composition, concentration, electric flied, and collect distance. We successfully blend PVDF and Pluronic F127 by electrospinning skill through optimizative parameters same as electrospinning PVDF film. Scanning electron microscope (SEM) was used to examine the surface morphology of the film. The films were further analyzed by thermal differential scanning calorimeter (DSC) and thermogravimetric analysis (TGA), activated partial thromboplastin time (APTT), prothrombin time (PT), protein and blood platelet adhesion. In addition, L929 fibroblasts cells were cultured on the surface and the cell number was determined by the MTT testing.
The results showed that the fiber diameter of electrospinning PVDF-F127 film was 205nm with average pore size 0.1μm. The adsorption of protein and platelet on electrospinning PVDF-F127 decreased significantly. In the cell culture of L929 fibroblasts, the amount on electrospinning PVDF-F127 film was higher than pure electrospinning PVDF film.

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