由於禿頭人口增加，治療禿頭已經成為重要的醫療項目之一，目前國內外治療雄性禿的方式主要分為口服用藥(fenasteride)、外用生髮水(minoxidil)、佩戴假髮與進行植髮手術。近年研究發現，將混合的真皮乳突細胞與表皮細胞植入禿髮處，可促進毛囊再生。所以本研究擬設計一個植入裝置加快植入速度、控制植入細胞量、將細胞做方向性的堆疊與降低手部負擔，本研究開發具有可以同時注射兩種細胞並進行堆疊且運用氣動快速注射的細胞植入器。
氣動式雙細胞堆疊植入器的設計概念是將各個部分分離，僅讓手部持最低重量的裝置，而其他控制的部分都分離開手部進行動作。我們將兩種細胞裝填於針筒內，將針筒安裝於注射量控制裝置上，藉由直線步進馬達將所需細胞量推入手持裝置中，細胞會在手持裝置中進行堆疊，最後使用氣動裝置輸出氣體將手持裝置內的細胞推入植入體。氣動式雙細胞堆疊植入器之各零組件於3D繪圖軟體中繪製完成後，注射量控制裝置部分直接以FDM製作成品，手持注射裝置部分先以ProJet列印出模型進行參數測試後使用壓克力加工成成品，最後將整體組裝並利用紅色與藍色兩種顏色之染劑分別做為兩種細胞之模擬進行測試。測試結果發現氣動式雙細胞堆疊植入器能夠成功達成兩種細胞於同一位置之植入並做堆疊，並可以依照需求控制兩種細胞植入量且可以根據使用量的不同輕易的更換使用的針筒。與前代裝置相比此帶植入裝置大幅地降低手持裝置的重量且不須額外人體施力。

With the increasing numbers of alopecia, how to treat alopecia has become an important issue. The general treatments of alopecia include finasteride, minoxidil, wear a wig and hair transplantation. Recent studies have found that implanting mixtures of dermal papilla cells and epidermal cells into bald areas could promote hair follicle regeneration. However, no suitable implanter exists. Therefore, this research planned to develop a pneumatic dual-cell stacking implanter to shorten the implanting time, to control the numbers of cell, to stack the cells, and to reduce the burden of hands.
Pneumatic dual-cell stacking implanter separated the control part from the handheld device to minimize the loading of hands. Two kinds of cells were filled in two syringes and the syringes were attached to the volume control system. The cells extruded to the handheld device with the help of liner step motor, the cells were stacked in the handheld device and push into body by pneumatic device. The components of the implanter were designed in the 3D CAD software .The control system was fabricated by FDM (Fused Deposition Modeling). The handheld device was tested by Projet model and fabricated the finished products by acrylic. The prototype was used to perform simulated implantation tests with red and blue dyes. The results showed that the pneumatic dual-cell stacking implanter can successfully implant and stack two kinds of cells into the same areas. Different size of syringe can be used according to various implant volumes. Comparing with the previous generation implanter, the handheld device is lighter and no extra loads are needed by hand.

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