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研究生： 廖文晢
Wen-Che Liao
論文名稱： 金屬玻璃鍍層應用於病理切片刀及刺青針之性能提升研究
ffects of Thin-film Metallic Glass Coatings on the Performance of Microtome blades and Tattoo needles
指導教授： 朱瑾
Jinn P. Chu
口試委員: 黃仁勇
Ren-Yeong Huang
曾元生
Yuan-Sheng Tseng
姚栢文
Pak-Man Yiu
學位類別： 碩士
Master
系所名稱： 工程學院 - 材料科學與工程系
Department of Materials Science and Engineering
論文出版年： 2020
畢業學年度： 108
語文別： 英文
論文頁數： 120
中文關鍵詞： 病理切片刀 、刺青針具 、金屬玻璃鍍層
外文關鍵詞： Microtome blades, Tattoo needles, TFMG
相關次數： 點閱：169  下載：0 
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    • 致謝 I 摘要 II Abstract III Contents IV List of Figures VII List of Tables XI Chapter 1. Introduction 1 1.1 An overview of thin film metallic glass 1 1.2 Motivation and Objectives 1 Chapter 2. Literature Review and Background 2 2.1 Introduction of Microtome Blade 2 2.1.1 Classification of Microtome Blade 2 2.2 Introduction of Tattoo 3 2.2.1 Stages of Tattoo Healing Process 6 2.2.2 Classification of tattoo needle 7 2.2.3 Tattoo needle issue 8 2.3 Metallic Glass 8 2.3.1 Adhesion and hardness characteristic 9 2.4 Thin Film Metallic Glass (TFMG): Characteristic and Fabrication 12 2.4.1 Lower Coefficient of Friction (CoF) 13 2.4.2 Biocompatibility and Antibacterial application 15 2.4.3 Sharpness and Durability Improvement 17 2.5 High power impulse magnetron sputtering (HiPIMS) 19 Chapter 3. Experimental Procedures 20 3.1 Sample Preparation 21 3.1.1 Microtome Blade Preparation 21 3.1.2 Polymer composition analysis (Raman Spectroscope) 21 3.1.3 Tattoo Needle Preparation 21 3.1.4 Polishing and Grinding of AISI-314 Stainless Steel Plates 22 3.1.5 Thin Film Metallic Glass (TFMG) Deposition 22 3.2 Characterizations of TFMG 24 3.2.1 Crystallographic analysis 24 3.2.2 Microstructure analysis 24 3.2.3 Chemical Composition Analysis (EPMA) 25 3.2.4 Hardness measurement (Nanoindentation system) 25 3.2.5 Surface Roughness Observation (Grinding and polishing machine) 25 3.2.6 Hydrophobic property (Contact angle) 26 3.3 Characterizations of Tattoo Needle and Machine 26 3.3.1 Surface Roughness Analysis of Tattoo Needle (confocal microscopy) 27 3.4 Cutting and Insertion Tests (MTS) 27 3.4.1 Test Material: Pork muscle and pork skin 28 3.4.2 Surface Morphology Observation of Pork skin (confocal microscopy) 29 3.4.3 Condition of Pigment coloring (Image J) 29 3.4.4 Cell adhesion Observation of Tattoo Needle (Fluorescent microscope) 29 3.5 Animal Tests 31 3.5.1 Animal Preparations 31 3.5.2 Condition of Pigment coloring 32 3.5.3 Histopathology analysis 32 Chapter 4. Results and Discussion 33 4.1 TFMG deposition 33 4.1.1 Crystallographic Analysis (XRD) 33 4.1.2 Chemical Composition Analysis (EPMA) 34 4.1.3 Surface Hardness Analysis ((Nanoindentation system) 34 4.1.4 Hydrophobic property (Contact angle) 35 4.2 Influences of Microtome blade Characteristics 36 4.2.1 Cutting Test Result against Pork– Microtome blade 37 4.3 Influences of Tattoo Needle Characteristics 43 4.3.1 Hydrophobic property (Contact angle) 43 4.3.2 Surface Roughness 45 4.3.3 Results of Insertion Test - Needle Sample: RL30 5-Needles 47 4.3.3.1 Needle-Body Observation (Adhesion area analysis-SEM) 49 4.3.4 Results of Insertion Test - Needle Sample: RL30 9-Needles 53 4.3.4.1 Needle-Body Observation (Adhesion area analysis-SEM) 56 4.4 Influences of Pork Skin Characteristics 59 4.4.1 Pork skin Wound analysis 67 4.4.2 Pigment coloring condition 67 4.5 Animal Test 70 4.5.1 Condition of Pigment coloring 70 4.5.2 Pathological Histology observation 85 4.5.2.1 Condition of Wound healing 99 4.5.2.2 Tattoo pigment distribution 100 4.5.2.3 Allergic reactions in animal test 100 4.6 Discussion 101 Chapter 5. Conclusions 103 References 104

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