本研究裝置為一套新的可變體積-附視窗暨影像處理系統的高壓相平衡分析裝置並採用合成法進行實驗系統測試，首先應用於H2O + 2-butoxyethanol，C4E1 (液液)與CO2 + 1-octanol(汽液)系統的相邊界觀測，結果顯示本實驗設備所量取的相邊界數據與文獻值相當吻合；繼而觀測抗溶劑二氧化碳與共溶劑DMSO與1,4-dioxane兩組雙成分系統的汽液平衡數據，且可準確地量測臨界點附近之相邊界，釜內容積最小約35 cm3 最大約60 cm3，平衡溫度介於313.15 K ~ 348.15 K，操作壓力1 MPa ~ 35 MPa。
將實驗所量取的混合物雙成份系統之汽液相平衡數據使用Soave-Redlich-Kwong、Peng-Robinson與Patel-Teja狀態方程式配合MR-Q1（單交互作用參數之凡得瓦爾單一流體混合律）與MR-Q2（雙交互作用參數之凡得瓦爾單一流體混合律）二種不同的混合律，同時以臨界區附近的數據為基準，採用驟沸計算訂定出最適化交互作用參數值。
本實驗之結果有助於了解超臨界流體應用於微粒製備的基礎性質，以及掌控造粒之關鍵條件。由實驗量取臨界點附近的數據，對於熱力模式的改善也會有很大的助益。

With synthetic method, a new high-pressure phase equilibrium analyzer (PEA) apparatus with a visual cell of variable volume ranging between 35 and 60 cm3 was set up in this study for determining the phase boundaries at condition up to near critical region. This apparatus was tested by measuring both the liquid-liquid (H2O + 2-butoxyethanol, C4E1) and the vapor-liquid (CO2 + 1-octanol) phase boundaries at elevated pressures. Good agreement between our experimental data and literature data was obtained. The apparatus was then used for observing the phase change of mixtures. The vapor-liquid equilibria (VLE) of carbon dioxide + dimethyl sulfoxide (DMSO) and carbon dioxide + 1,4-dioxane at temperatures from 313.15 K to 348.15 K and pressures from 1 MPa to 35 MPa were measured.
The experimental VLE data were correlated by the Soave-Redlich-Kwong, the Peng-Robinson and the Patel-Teja equations of state with the van der Waals one-fluid one-parameter mixing rule (MR-Q1) and the van der Waals one-fluid two-parameter mixing rule (MR-Q2). The binary interaction parameters were determined from the flash vaporization calculation based on the experimental data of the critical region.
The results are of importance to our understanding of the formation of nano- particles by means of the supercritical anti-solvent process. The experimental data for the region near the critical point are needed for improving the equations of state.

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中文部分
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龔皇誌(Gong)，"超臨界二氧化碳抗溶劑與溶劑之汽液平衡"，碩士論文，國立台灣工業技術學院化工系，民國九十三年。