The persistent need to fight against and/or manage various diseases that affect the general human population around the world comes with a large increase in healthcare expenditure. To contain the ever-increasing healthcare costs while providing high-quality medical services, there is need to eliminate healthcare waste by regularly redistributing resources from low-value towards high-value healthcare technologies. This process of health technology management can be achieved by routinely reassessing the value of technologies in current use by means of an evidence-based approach called health technology reassessment. In spite of the fact that a framework to conduct health technology reassessment exists, limited practical experience has been reported. To this end, this dissertation contributes to the literature by adding to this knowledge gap, a practical health technology reassessment for hepatitis B virus screening tests for blood donors Taiwan. The results of this study report on the performance of the existing HBV screening strategy in Taiwan. Furthermore, the results suggest that value of the HBsAg testing is in doubt in a setting where NAT is in use. Nevertheless, HBsAg testing remains the preferred choice when the blood providers have extremely limited budgets and cannot afford to use NAT.

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