The rising price of crude oil and global warming have received much attention recently. Due to these factors, improving energy efficiency has become an essential objective of chemical process research. In order to reduce energy consumption and enhance overall controllability, the liquid side stream arrangement is frequently referred to as the vapor-liquid interconnection in thermally coupled distillation. This work combines the side stream arrangement with the development of thermally coupled configuration to improve the economic benefits. This work proposes a thermally coupled arrangement with one side stream (Case 1) and two side streams (Case 2) to improve energy efficiency simultaneously. Subsequently, the hybrid heat-integrated configuration will combine with one side stream (Case 3) and two side streams (Case 4). The sequential iterative method was used to optimize the fourth proposed design, which minimizes the Total Annual Cost (TAC). Compared with the conventional configuration, the hybrid heat integration with a two-side stream configuration (Case 4) has the optimal results. It can eliminate the remixing effect and save 47.27% energy and 31.46% TAC. Moreover, the control structure was applied to the case 4 in order to maintain product quality and process safety. Four proposed control structures are CS1, CS2, CS3, and CS4, which will be applied to the case 4. From all the proposed control structures, CS4 is an excellent control structure for maintaining feed and composition throughput disturbances with an indication of the smallest IAE value. The IAE values in case 4 are ±10% feed disturbance at DPC 0.001% and 0.002%, ± 10% feed disturbance at MA 0.06% and 0.0015%. ±5% composition disturbance at DPC 0.0005% and 0.001%, ±10% composition disturbance at MA 0.0033% and 0.0067%. It is indicated, the overshoot can be well maintained when a feed and composition throughput disturbance occurs.

The rising price of crude oil and global warming have received much attention recently. Due to these factors, improving energy efficiency has become an essential objective of chemical process research. In order to reduce energy consumption and enhance overall controllability, the liquid side stream arrangement is frequently referred to as the vapor-liquid interconnection in thermally coupled distillation. This work combines the side stream arrangement with the development of thermally coupled configuration to improve the economic benefits. This work proposes a thermally coupled arrangement with one side stream (Case 1) and two side streams (Case 2) to improve energy efficiency simultaneously. Subsequently, the hybrid heat-integrated configuration will combine with one side stream (Case 3) and two side streams (Case 4). The sequential iterative method was used to optimize the fourth proposed design, which minimizes the Total Annual Cost (TAC). Compared with the conventional configuration, the hybrid heat integration with a two-side stream configuration (Case 4) has the optimal results. It can eliminate the remixing effect and save 47.27% energy and 31.46% TAC. Moreover, the control structure was applied to the case 4 in order to maintain product quality and process safety. Four proposed control structures are CS1, CS2, CS3, and CS4, which will be applied to the case 4. From all the proposed control structures, CS4 is an excellent control structure for maintaining feed and composition throughput disturbances with an indication of the smallest IAE value. The IAE values in case 4 are ±10% feed disturbance at DPC 0.001% and 0.002%, ± 10% feed disturbance at MA 0.06% and 0.0015%. ±5% composition disturbance at DPC 0.0005% and 0.001%, ±10% composition disturbance at MA 0.0033% and 0.0067%. It is indicated, the overshoot can be well maintained when a feed and composition throughput disturbance occurs.

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