氯丁橡膠為第一批發明出來的合成橡膠，其各種性質兼備，以致於從發明到現今社會都還在使用，也因為其泛用性，短時間內人類社會無法不去使用。環保意識日漸發展的現今，對於影響人類健康的化合物，人們也提出應該要禁用某些材料。
歐盟於2007年6月起實施「新化學品政策」(Registration, Evaluation, Authorisation and Restriction of Chemical Substances, REACH)，針對具人體健康或環境危害性之化學物質進行初步篩選評估，並公告「高度關注物質候選清單」(Candidate List of Substances of Very High Concern, SVHC)，若清單物質經審查認定有害，則該物質需申請許可，獲得授權後方可使用或置入歐盟市場[1]。
本研究選用選用Ethylene thiourea(ETU)、N,N'-phenylene dimaleimide(PDM)、N, N'-dibutyl thiourea (DBTU)三種交聯劑，首先以微型混煉機依配方製作出橡膠試片，透過硫化曲線及木尼黏度測試，分析不同填料份量及種類之硫化膠性質，再透過物理機械性質分析比較配方間差異，如比重、硬度、拉伸強度、撕裂強度、熱老化、耐油性、耐磨耗以及永久壓縮變形率。
由實驗得知PDM在應力強度上、耐老化特性、耐磨耗特性、抗壓縮變形上都有突出的表現。其無硫分子式，對於氯丁橡膠交聯結構中帶有C-C鍵結幫助橡膠整體強度增強，與含硫交聯劑相比下有競爭力。

Neoprene was the first synthetic rubber invented. It has all kinds of properties, so that it is common used until now. Because of its versatility, it won’t vanish in a short time. And with the growing awareness of environmental protection, people have also suggested that certain compounds that affect human health should be banned.
The European Union implemented the "Registration, Evaluation, Authorisation and Restriction of Chemical Substances (REACH)" in June 2007, conducted preliminary screening and evaluation of chemical substances with human health or environmental hazards, and announced "high concern "Candidate List of Substances of Very High Concern (SVHC)", if the substances in the list are found to be harmful after review, the substance needs to apply for a permit and can only be used or placed on the EU market after obtaining authorization.
In this study, three cross-linking agents, ETU, PDM, and DBTU, were selected. First, a rubber test piece was prepared according to the formula using by micro-mixer. The vulcanization curve and the Mooney viscosity test were used to analyze the properties of vulcanizates with different filler contents and types. Analysis of physical and mechanical properties compares differences between formulas, such as specific gravity, hardness, tensile strength, tear strength, heat aging, oil resistance, abrasion resistance, and compression deformation rate.
It is known from experiments that PDM has outstanding performances in stress intensity, aging resistance, wear resistance and compression resistance. Its sulfur-free molecular formula puts C-C bonding in the crosslinked structure of chloroprene rubber to help strengthen the overall strength of the rubber, which is competitive with sulfur-containing crosslinkers.

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