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研究生: 王絢姻
Syuan-yin Wang
論文名稱: 乳房病變仿體組織力學特性
Mechanics of Pathological Breast Tissue Phantom
指導教授: 廖崇禮
Chung-li Liao
廖國基
Kuo-chi Liao
口試委員: 劉見賢
Chien-hsien Liu
顏炳郎
Ping-lang Yen
學位類別: 碩士
Master
系所名稱: 工程學院 - 機械工程系
Department of Mechanical Engineering
論文出版年: 2011
畢業學年度: 99
語文別: 中文
論文頁數: 47
中文關鍵詞: 乳房腫瘤超彈性材料有限元素分析
外文關鍵詞: breast tumor, hyperelasticity, finite element analysis
相關次數: 點閱:309下載:1
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乳房腫瘤勁度大於周邊脂肪組織勁度,惡性腫瘤勁度亦高於良性者,因此經常藉由探測乳房局部勁度之差異,判斷組織內是否內含腫瘤與其之良惡性。本研究採用有限元素分析,探討複合仿體於探測過程承受不同負荷之反應。藉由仿體組織與仿體腫瘤於承受單軸壓縮實驗條件下,獲得描述仿體機械性質之超彈性材料組成律所需參數,並經由複合仿體之壓痕分析與相對應實驗比對驗證其合宜性。接續透過橫移分析與橫移實驗檢視複合仿體於探測過程承受負荷情形,藉以瞭解乳房腫瘤於探測過程承受負荷情形。結果顯示數值模擬結果之力量-位移曲線特徵寬度雖略大於實驗結果,其力量峰值預測仍具備相當準確性。並檢視仿體腫瘤直徑大小與埋置深度於橫移條件下,對於探頭承受負荷之影響。


The existence of breast tumors and whether they are benign or malignant is preliminarily judged by differences in stiffness through the probing procedures. In the current study, a finite element analysis was conducted to investigate the reaction of breast phantoms under various loading conditions. A hyperelasticity model was adopted to describe responses of different phantoms, and the corresponding required parameters in the model were evaluated from measurements of the phantom under uniaxial compressive tests. Composite phantoms were fabricated by embedding the phantom tumor into the phantom tissue. Indentations of the composite phantom based on the experiment and those based on the simulation were compared, and the suitability of the selected model was validated. Lateral exploration of the composite phantom was subsequently performed. The stiffness and size of the phantom tumor can be characterized by the profile of relationships between the reaction force and the transverse displacement of the probe. Effects of the size and embedded depth of the phantom tumor on the reaction of the probe were examined as well.

誌謝.................................I 中文摘要............................II Abstract...........................III 圖目錄..............................VI 表目錄..............................IX 第1章緒論............................1 1.1前言............................1 1.2文獻回顧........................1 1.3研究目的........................5 1.4論文架構........................6 第2章實驗............................8 2.1樣品製作........................8 2.2實驗儀器.......................17 2.3實驗方法與結果.................23 2.3.1單軸壓縮實驗 .................23 2.3.2壓痕實驗.....................25 2.3.3橫移實驗.....................26 2.3.4時間效應.....................27 第3章有限元素分析...................29 3.1壓痕分析.......................32 3.2橫移分析.......................35 第4章結論與未來展望.................43 參考文獻............................45

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