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| 研究生： |
張家榮 Chia-Jung Chang |
|---|---|
| 論文名稱： |
磁振頻譜影像後處理分析的加速與整合探討 Computation Acceleration and Integration in Magnetic Resonance Spectroscopic Imaging (MRSI) Post-processing and Analysis. |
| 指導教授： |
林益如
Yi-Ru Lin |
| 口試委員: |
黃騰毅
Teng-Yi Huang 林發暄 Fa-Hsuan Lin 蔡尚岳 Shang-Yueh Tsai 莊子肇 Tzu-Chao Chuang |
| 學位類別： |
碩士 Master |
| 系所名稱： |
電資學院 - 電子工程系 Department of Electronic and Computer Engineering |
| 論文出版年： | 2011 |
| 畢業學年度： | 99 |
| 語文別： | 英文 |
| 論文頁數： | 72 |
| 中文關鍵詞： | 磁振頻譜 、後處理 、曲線凝合 |
| 外文關鍵詞： | PEPSI, MRS Post- processing, Signal filtering, Phase correction |
| 相關次數： | 點閱：262 下載：6 |
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磁振頻譜 (MagnDetic Resonance Spectroscopy) 是一種藉由觀察各種不同代謝物本身的頻譜來分析的方法。在頻譜上，各種代謝物 (NAA, creatine, choline and glx) 都有其自己獨特的位置以及含量，藉由觀察頻譜及定量可以來探討受試者或是病人體內的病變。
在磁振頻譜的處理中，最重要的部分就是後處理 (Post-processing)。後處理主要是在將原本得到的訊號經過一系列人為的校正之後，還原出頻譜應有的樣貌。原本的訊號有太多的雜訊，隨著時間的流逝，訊號衰減掉但雜訊仍然存在，所以後處理就是將原本充滿雜訊與影響頻譜品質的因素去除的動作。看似簡單的處理實則花費不少的時間，在本論文當中會探討在我們磁振頻譜研究中有運用到的後處理方法，例如水訊號的抑制、雜訊濾除、相位校正，以及如何提升整體的運算速度同時保有原本的精準度。最後會提到如何更即時的運用在臨床研究上面。
LCModel是一套在分析MRS各種資訊且具有公信力的軟體，但是相對的耗時，成本也比較高。本論文將會提到如何運用MATLAB演算法來分析頻譜的曲線凝合以及與LCModel的結果比較。藉以達到能在沒有LCModel的情況下也能做基本但又不失準確性的分析。
Magnetic resonance spectroscopic (MRS) has been widely applied in clinical experiment and research for many years, and can provide correct, clear and reliable spectrum result for researchers to observe metabolites, such as NAA, creatine, choline and glx. By applying rapid RF sequence, such as Proton Echo Planar Spectroscopy Image (PEPSI), the data acquisition time can have significant reduction. The most important part in MRS research is post-processing, which can decide the completeness of final result by adjusting different methods into procedure like eddy current correction, removal of the water signal, signal filtering, zero filling, phase correction and baseline correction. But not all of the methods were included in our research; instead our research is tend to obtain the balance between accuracy and speed acceleration.
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