本研究中，將實驗分為兩部分，先以不同濃度(6%，8%，10%，12%，14%)之聚乙烯醇(PVA)以冷凍-解凍法製備高強力水膠，再透過FTIR、XRD、DSC、TGA、含水率與膨潤性質分析等對材料的基本結構與性能進行分析。再將聚乙烯醇(PVA)添加不同分子量(M.W.3500，8000，58000，1300000)之聚乙烯基吡咯烷酮(PVP)用物理性交聯法製備聚乙烯醇(PVA)/聚乙烯基吡咯烷酮(PVP)共混水膠，利用FTIR、XRD、DSC、TGA、含水率與膨潤測試等對材料的結構與性能進行分析表徵，並研究了材料的力學性能與細胞毒性。結果表明，PVP能與PVA通過氫鍵形成分子級混合的PVA/PVP共混水膠。
結果表明力學性質隨聚乙烯醇(PVA)濃度提高而增加，而水膠含水率隨聚乙烯醇(PVA)濃度提高而下降。聚乙烯基吡咯烷酮(PVP)之分子量可以影響聚乙烯醇(PVA)水膠的結構、結晶度、玻璃化轉移溫度、吸水率以及力學性質。結果顯示力學性隨聚乙烯基吡咯烷酮(PVP)之分子量增加而增加，吸水率及膨潤率隨聚乙烯基吡咯烷酮(PVP)之分子量增加減小。
聚乙烯基吡咯烷酮(PVP)使該共混水膠具有高的力學強度與吸水率和良好的細胞相容性，而且具有類似天然組織的可滲透性。PVP/PVA共混水膠是一種有發展前景的生物醫學材料。

In this study, the high strength of hydrogel prepared from poly (vinyl alcohol) and poly(N-vinyl pyrrolidone). Poly (vinyl alcohol) hydrogel were first prepared by freezing and thawing method. The effects of various factors on the mechanical and swelling properties of the PVA hydrogel were investigated. The tensile strength and average tensile modulus of PVA hydrogel both increase as the concentration of PVA aqueous solution. The research of swelling dynamic and water content behavior shows that it decreases with the increasing PVA hydrogel concentration.
In the present work, blend hydrogels based on PVA and different molecular weight of poly (vinyl pyrrolidone) (PVP) were prepared by repeated freezing and thawing method. Such hydrogel had similar internal three-dimensional structure and water content approximately 300(%) .
The poly (vinyl alcohol)/poly (N-vinyl pyrrolidone) (PVA/PVP) hydrogels were prepared by CO-solution method and treated with repeated freezing and thawing method. The composite material was analyzed by infrared spectroscopy, X-ray diffraction, differential scanning calorimeter. Its water absorption, swelling ratio, and mechanical property were also tested. The results show that PVP can chemically bond with PVA and form composite hydrogel with PVA in molecular level. The different molecular weight of PVP can affect the micro structure, crystalinity, glass transition temperature, water absorption, swelling ratio and mechanical property of PVA hydrogel .The PVP/PVA hydrogel has high water content and mechanical property.
The tensile strength and average tensile modulus of PVA/PVP hydrogel both increased with the increase of the molecular weight of PVP. The research of swelling dynamic and water content behavior shows that it decreases with the increase of the molecular weight of PVP.

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