鎳鈦膽道支架(Nitinol Biliary Stent)為一種中空管狀結構的醫療器材，可將其壓縮到運輸系統(Delivery System)內，經由內視鏡的工作通道(Working Channel)放置到因腫瘤而窄化之病灶處，鎳鈦支架由運輸系統釋放後能因人體溫度自行撐開窄化之病灶，因此又稱自擴型膽道支架(Self-Expandable Biliary Stent)。
　　本研究使用ANSYS輔助分析開發出能壓縮到5 French(Fr，約等於1.66 mm)運輸系統內之鎳鈦支架後，使用光纖雷射加工2 mm鎳鈦合金管材，並搭配濕式切割降低因雷射導致的熱影響，成功加工出線寬120 μm之鎳鈦支架。本研究採用不同的加熱時間探討鎳鈦支架擴張後的回縮量，並搭配本研究設計之擴張模具與壓克力遮罩，在僅提供支架徑向力的情況下擴張鎳鈦支架，成功將鎳鈦支架均勻擴張至直徑12 mm，接著使用錐度棒與支架壓縮器控制鎳鈦支架的壓縮量，並在結構完整的情況下將鎳鈦支架壓縮到5 Fr矽膠管內，最後將壓縮完成之鎳鈦支架釋放到36℃之水中，模擬鎳鈦支架在人體內擴張之情況，結果發現鎳鈦支架自行擴張到11.5 mm， 整體結構完整，沒有因壓縮而受到損壞或變形。

A Nitinol biliary stent is a medical device with hollow tube structure and used to deal with the bile duct obstruction. It is crimped into a delivery system, deployed to tumor or obstructive position, then expanding by itself to dilate the blockage of bile duct.
In this study, ANSYS was used to develop a biliary stent that can be crimped in a catheter with 5 French (Fr) diameter and expanded to 12 mm diameter. Nanosecond fiber laser was determined to cut a 2 mm diameter Nitinol tube to fabricate the designed biliary stent. A wet laser cutting method was applied to reduce heat affected zone (HAZ), and stents with strut width 120 μm were successfully fabricated.
In addition, this study investigated the retraction rate of expanded stents with different heat treatment time and temperature. A stent expanding tool was designed and applied to expand stents to 12 mm diameter uniformly, with only radial expanding force. After that, the expanded stents were crimped into 5 Fr catheters and then released. The results showed the released stents could self-expand to more than 11.5 mm easily and their struts were all in good shape, without any significant damage.

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