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研究生: 蘇柏豪
Bo-Hao - Su
論文名稱: 血壓波子波訊號分析
Hemobarogram Subwave Component Pulse Signal Identification
指導教授: 張以全
Peter I-Tsyuen Chang
口試委員: 劉孟昆
Meng-Kun
張春梵
mailto:chunfan.chang
學位類別: 碩士
Master
系所名稱: 工程學院 - 機械工程系
Department of Mechanical Engineering
論文出版年: 2017
畢業學年度: 105
語文別: 中文
論文頁數: 80
中文關鍵詞: 血壓波非線性希爾伯特-黃轉換心血管疾病
外文關鍵詞: Hemobarogram
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  • 在現今飲食裡,很容易出現多醣、多油、重鹹……等情形,長期這樣的飲食習慣又不常去運動代謝的情況下,容易造成糖尿病、心臟病……等心血管疾病,如果不去注意而忽略下,容易造成死亡,況且心血管疾病是國人十大死因之一。

    所以要多瞭解及照顧自己身體,我們更要隨時量測及監控我們的血壓。量血壓方式很多種,較容易取得的血壓計,基本上只會出現舒張壓、收縮壓跟平均血壓,若在高級一點的電子血壓計可以連接電腦,使用專門的軟體取得個人的血壓波形,但一般人在血壓波形上很難得到一些資訊,不外乎就與其他健康人的波型,去比較最高峰的數值高低與單一血壓波開始到結束的時間長短而已。

    但張春梵教授將使用電子血壓計量測到的連續血壓波形,利用非線性希爾伯特-黃 轉換演算法和訊號系統的經驗模型分析,分解出兩種訊號-連續能量加入形式的生產機制與能量消散形式的削減機制訊號,其中指尖血壓波的生產、削減機制已經可以對應至手腕饒動脈與心臟主動脈的血壓波形。

    因為上述生產機制和削減機制訊號是連續的,也都藏有一些資訊,所以本論文利用這些連續訊號,來做自動化的分段、找點、擬和、分析。


    Diets today tend to be over-seasoned with sugar, grease and salt. Those who don’t exercise could end up having diabetes and other serious heart diseases. Heart disease is one of the ten leading causes of death in Taiwan. If we don’t pay close attention to our diet, the consequences could be fatal.

    In order to take better care of our health, we should take and monitor our blood pressure closely. There are several different ways to measure our blood pressure: blood pressure meter is the most accessible, it simply tells us our diastolic, systolic and average blood pressure, electric sphygmomanometer is a more advance device, it can be connected to a computer, using specialized software to acquire personal blood pressure wave. However, it is hard for most people to get information out of blood pressure wave, mostly just compare theirs with another’s, and see if there are differences between the peak, crest and the wavelength of their waves.

    Nevertheless, professor chunfan-chang,using Hilbert-Huang Transform method and the empiric model of signal system to analyze, has dissected the continuous blood pressure waveform into two signals: Generator of production mechanism and Dissipator of reduction mechanism. The production and reduction mechanism of fingertip hemobarogram can even correspond to the blood pressure waveform of wrist radial artery and cardio aortic.

    Due to the hidden information in the continuation of production and reduction mechanism from above, the study has used these continuous signals to automated section, find characteristic point, fit and analyze.data sources.

    論文摘要..........I Abstract.........II 誌謝.....III 目錄.....IV 圖目錄...VI 表目錄...X 1 緒論.....1 1.1 前言.....1 1.2 血壓計回顧........5 1.3 研究目的....7 2 血壓波背景介紹.....9 2.1 心臟.....9 2.2 血管.....11 2.3 心臟到左手指端血管概要.....12 2.4 特徵點意義.......14 2.5 總程式介紹.......17 3 程式設計與流程...18 3.1 峰值選擇.18 3.1.1 模擬設置.19 3.1.2 模擬比較.21 3.2 正規化.24 3.2.1 目的....24 3.2.2 方法....25 3.2.3 正規化流程圖.....27 3.3 特徵點提取.......28 3.3.1 參考波....28 3.3.2 方法......31 3.3.3 特徵點提取流程圖...37 3.4 結果......38 4 結論與未來展望....39 4.1 結論....39 4.2 未來展望...39 參考文獻..40 附錄A:MATLAB 程式列表....41 A.1 主程式......41 A.2 峰值選擇....43 A.3 正規化.....44 A.4 選取特徵點..45 A.5 波峰.......47 A.6 波谷.......57 附錄B:單一次心跳特徵點圖...68

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    [9] M. Elgendi, “On the analysis of fingertip photoplethysmogram signals,” Current cardiology reviews, vol. 8, no. 1, p. 14, 2012.

    [10] J. R. Mitchell and J.-J. Wang, “Expanding application of the wiggers diagram to teach cardiovascular physiology,” Advances in physiology education, vol. 38, no. 2, pp. 170–175, 2014.

    [11] K. V. Madhav, M. R. Ram, E. H. Krishna, N. R. Komalla, and K. A. Reddy, “Estimation of respiration rate from ecg, bp and ppg signals using empirical mode decomposition,” in Instrumentation and Measurement Technology Conference (I2MTC), 2011 IEEE, pp. 1–4, IEEE, 2011.

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