本研究探討三價金屬離子（Fe3+和Cr3+）和二價金屬離子（Cu2+、Ni2+和Co2+）與配位體棓酸、L-己氨酸和菸鹼酸之平衡常數。利用pH電位滴定法在25℃水溶液（I=0.15之硝酸鈉）下，探討金屬離子和配位體之二元和混合錯合物。為了探討穩定常數，本研究也一併探討自由配位體之質子化常數。利用電位滴定所測得之數據代入“HYPERQUAD2008“之軟體以建立各系統中錯化作用之模式，並且以紫外分光光度計進行定性確認各溶液中形成之錯和物。
本研究也討論各系統中所發現之現象。在金屬離子之性質方面，穩定常數的趨勢是 Cu2+> Ni2+> Co2+，此與歐文-威廉之二價金屬離子順序吻合。至於三價金屬離子，Fe3+之穩定常數永遠高於Cr3+。在配位體方面，當系統含有棓酸作為配位體時，比其他不含棓酸之系統穩定。本研究並利用∆log K進行混合配位體與二元錯合物穩定性之定量比較。

The equilibrium constants for trivalent metal ions (Fe3+ and Cr3+) and divalent metal ions (Cu2+, Ni2+ and Co2+) with ligands gallic acid, L-norleucine and nicotinic acid were reported in this work. The binary and mixed ligand complexes between those metal ions and ligands were studied by using pH-potentiometric titration in aqueous solution at 25oC (I = 0.15M NaNO3). In order to determine the stability constant values, the protonation constants of free ligands were also determined. The complexation model for each system was established by the software program “HYPERQUAD 2008” from potentiometric titration data. UV spectrophotometric measurement was carried out to confirm the complex that formed in each solution qualitatively.
The phenomenon that occurred in each system was discussed. In terms of the nature of metal ion, the trend of stability constant is Cu2+ > Ni2+ > Co2+, which is in agreement with the Irving-William order of divalent metal ions. For trivalent metal ions, stability constant of Fe3+ is always higher than that of Cr3+. In terms of the ligand, the system that contains gallic acid as a ligand is more stable than the other systems that do not contain gallic acid. The stability of mixed ligand complexes was quantitatively compared with corresponding binary complexes in term of ∆log K.

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