本研究使用批式反應器探討由乙酸與異丙醇合成乙酸異丙酯合成反應之非均相反應動力行為，反應中使用酸性陽離子交換樹脂Amberlyst 39為觸媒。實驗操作於328.15 K至348.15 K之間，此外，並探討（醇/酸）進料莫耳比、觸媒質傳阻力以及觸媒添加量之效應。
反應動力實驗結果顯示，反應速率隨著反應溫度、（醇/酸）進料莫耳比、觸媒量加快；但轉速與觸媒粒徑對轉化率影響不大，而增加（醇/酸）進料莫耳比也會提升酸之平衡轉化率。經由吸附平衡實驗結果得知，乙酸異丙酯之合成反應中各成分於Amberlyst 39之吸附強度依序為水 > 乙酸 > 異丙醇 > 乙酸異丙酯。
乙酸異丙酯合成反應動力數據分別以理想溶液擬均相模式（IQH）、非理想溶液擬均相動力模式（NIQH）、Eley-Rideal（ER）模式、Langmuir-Hinshelwood-Hougen-Watson（LHHW）模式模式關聯，並求得最適化的動力參數值，NRTL模式則用於計算各反應成分之活性係數。關聯的結果顯示ER模式為描述乙酸異丙酯合成反應的非均相催化動力行為的最佳模式；惟吸附效應不顯著。

The heterogeneous kinetics behavior was investigated with a batch reactor for the synthesis of isopropyl acetate from acetic acid and isopropyl alcohol (IPA) over acidic cation-exchange resins, Amberlyst 39. The experiments were conducted at tempertures from 328.15 K to 348.15 K. Additionally, the effects of molar ratio of IPA to acetic acid in the feed stream, the mass transfer resistances, and the different levels of catalyst loadings on the catalytic reaction were also observed.
The reaction rate of acetic acid increased with increase of reaction temperature, molar ratio of IPA to acetic acid in the feed stream and catalyst loading, but rotational speed and the size of catalyst beads are minor factors. Moreover, the equilibrium conversion of acid increased with increase of reaction temperature and molar ratio of IPA to acetic acid in the feed stream. The relative adsorption strengths of the reacting species were determined by adsorption experiments. The results indicated that the magnitude of adsorption strengths on Amberlyst 39 followed the order of water > isopropyl acetate > acetic acid > IPA .
The kinetic data of the synthesis of isopropyl acetate were correlated with the ideal-quasi-homogeneous (IQH), the non-ideal-quasi-homogeneous (NIQH) the Eley-Rideal (ER), the Langmuir-Hinshelwood-Hougen-Watson (LHHW) models, respectively. The optimal values of the kinetic parameters were determined from the data fitting. The NRTL model was used to calculate the activity coefficients for each reacting species. The ER model yielded the best representation for the kinetic behavior of heterogeneous catalytic synthesis of isopropyl acetate, but the adsorption effect is minor.

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