近年來，人們越來越重視晝夜節律的相關研究。Jeffrey Hall、Michael Rosbash與Michael Young三位遺傳學家因過去發現控制晝夜節律的分子機制，而獲得2017年的諾貝爾生理醫學獎。除了晝夜節律議題變得日益重要，也有許多研究指出，照明對現代人的生理、心理方面影響極為顯著。因此，兩者結合的「晝夜節律照明」，應用於辦公室工作者成為了重要的研究課題。在辦公室照明領域中，雖然已有標準來規範不同工作場域的照度，但辦公室照明對於人類健康的影響仍有深入討論的空間。
本研究以模擬一般辦公室場域及工作模式作為實驗架構，並基於晝夜節律刺激值(CS值)進行辦公室光源重建，再搭配國際標準CIE S 026 Toolbox的黑視素晝光效率比進行光源細部分析。再分別以腦電圖、心電圖、眼電圖與閃光融合閾值等生理訊號數據，以及搭配主觀視覺舒適度問卷之調查結果，探討32位辦公室工作者(16男16女，平均年齡28.00 ± 5.79歲)在進行三項辦公室任務時，其生理與心理之變化。
本研究成功驗證了晝夜節律刺激值(CS值)計算對於辦公室照明設計的可行性，並於結果中深入分析高CS值搭配高黑視素晝光效率比之照明，發現CS ≥ 0.45與較高的黑視素晝光效率比之照明可有效地幫助辦公室工作者減少視覺疲勞。因此，本研究以此分析結果提出減少辦公室工作者的視覺疲勞之照明設計方法。

In recent years, there has been an increased focus on research related to the circadian rhythm. Jeffrey Hall, Michael Rosbash, and Michael Young, three geneticists, were awarded the 2017 Nobel Prize in Physiology and Medicine for their past discoveries of the molecular mechanisms that control the circadian rhythm. In addition to the increasing importance of circadian rhythms, many studies indicate that lighting has a significant impact on modern humans' physiological and psychological aspects. Therefore, the "Circadian Lighting" that combines the two has become an important research topic for office workers. In the field of office lighting, although there are standards to regulate the illumination levels in different workplaces, there is still room for further discussion on the effects of office lighting on human health.
In this study, we simulated the general office field and working mode as the experimental framework, conducted the reconstruction of office light source based on Circadian Stimulus (CS), and then analyzed the light source details with Melanopic Daylight Efficiency Ratio (DER) of CIE S 026 Toolbox. The physiological signal data such as electroencephalogram (EEG), electrocardiogram (ECG), electrooculogram (EOG), and Critical Flicker Fusion Frequency (CFF), and the results of subjective visual comfort questionnaire were used to investigate the physiological and psychological changes of 32 office workers (16 males and 16 females, mean age 28.00 ± 5.79 years) when they performed three office tasks.
This study successfully verified the feasibility of Circadian Stimulus for office lighting design. The results analyzed the lighting with high CS and high Melanopic DER and found that the lighting with CS ≥ 0.45 and high Melanopic DER can effectively help office workers reduce visual fatigue. Therefore, this study proposes a lighting design method to reduce the visual fatigue of office workers based on the results of this analysis.

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