由於科技與醫學不斷的進步，人類平均壽命增加，各種因為老化所造成的疾病也伴隨而來，其中一個很好的例子就是退化性膝關節炎。治療退化性膝關節炎的方式有很多，臨床主要的治療方式有: (1)全膝關節置換術；(2)高位脛骨截骨手術。治療方式中，全膝關節置換術要切除骨頭為不可回復性，主要使用在晚期治療的方式，早期治療方式比較適用高位脛骨截骨手術，保留骨本，延長二次手剩的時間。
高位脛骨截骨手術是否成功就要看手術後骨板骨釘系統固定在骨頭上的穩定度。而常常造成手術失敗的原因是骨板骨釘系統的鋼性不夠而斷裂或是骨釘不能牢牢的咬住骨頭而鬆脫。造成手術失敗的問題主因是骨板骨釘系統的設計上不能穩定的固定在骨頭上。
本研究使用有限元素分析和生物力學實驗來研究不同形式的開口式高位脛骨截骨手術骨板骨釘系統固定在骨頭上的穩定度。使用有限元素分析四種不同型式的骨板骨釘系統之穩定情況和應力分布狀況。生物力學實驗主要測試兩種不同型式的骨板骨釘系統的穩定情況，重實驗的結果驗證那一種型式的骨板骨釘系統方式使用在手術上可以有更好穩固性，使得病人修口癒合更快，提高手術成功率。

Continuous progress of science, technology and medicine, the average human life expectancy increases, diseases caused by a variety of aging is also accompanied by a good example of knee osteoarthritis. There are many ways the treatment of osteoarthritis of the knee, clinical treatment: (1) total knee arthroplasty; (2) high tibial osteotomy. Treatment, total knee arthroplasty resection of bone for non-recovery of the main treatment in the late, early treatment for high tibial osteotomy, to retain bone mass, to extend the time the second hand left.
High tibial osteotomy surgery is successful depends on the bone plate bone screw system in the post-operative stability of bones. Often resulting in surgical failure because steel bone plate bone screw system is not enough to fracture or bone screws can not be firmly bite the bones and loose. Cause of surgical failure mainly due to the bone plate bone screw system design can not be stable in the bones.
In this study, using finite element analysis and biomechanical experiments to study the different forms of opening high tibial bone osteotomy surgery bone plate bone screw system stability bones. Using finite element analysis of four different types of bone plate bone screw system stability and stress distribution. The stability of the bone screw system of biomechanics experiments to test two different types of bone plates, heavy experimental results verify that a type of bone plate the bone screw system use of surgery can have better stability, making the patient to repair the wound healingfaster, improve the success rate.

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