研究生: |
田立德 Lester - Chan Lik Teck |
---|---|
論文名稱: |
盤尼西林發酵程序控制設計 Control Design for Penicillin Fermentation |
指導教授: |
周宜雄
Yi-Shyong Chou |
口試委員: |
錢義隆
I-Lung Chien 王逢盛 Feng-Sheng Wang 錢玉樹 Yu-Shu Chien |
學位類別: |
碩士 Master |
系所名稱: |
工程學院 - 化學工程系 Department of Chemical Engineering |
論文出版年: | 2006 |
畢業學年度: | 94 |
語文別: | 英文 |
論文頁數: | 103 |
中文關鍵詞: | 差值進化演算法 、模式預測控制 、最適化 、饋料式最適化 |
外文關鍵詞: | differential evolution, model predictive control, optimization, fed-batch optimization |
相關次數: | 點閱:433 下載:3 |
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盤尼西林是目前最廣泛應用的抗生素之ㄧ,盤尼西林通常以饋料批次生產。而饋料批次操作具有挑戰性因為它能提供進料基質不同的饋料方式,已達到生產的最適化需求,另外從控制的觀點,饋料批次的最適化進料方式是動態問題。
本研究的重點強調以模式為基礎的最適化控制設計,期望能補償系統因有參數變動,不確定等因素的影響原最適化的控制操作結果。本文主要利用差值進化法為最適化的主要工作,執行各項的最適化尋優工作,之後討論非線性輸出-輸入,適應控制和模式預測控制的設計與控制的成效。比較以上各種控制器在參數變動下的韌性控制結果。結果得到模式預測控制可以得到較滿意的結果。
Penicillin is one of the most widely used antibiotics and is used for many Gram-positive bacterial infections. The production of penicillin is usually operated in fed-batch mode. The optimization of a fed-batch process is challenging because it is a dynamical optimization process. In this work, the suitability of differential evolution as an optimization approach tested. Inspired by model predictive control, an algorithm was proposed to handle disturbance to a system. This incorporated differential evolution into the algorithm. Different cases were presented and the algorithm was able to perform satisfactorily.
References
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