在先前實驗室所發展的動態光罩快速成型系統中，使用PCL-PEG-PCL生醫材料混合光交聯劑PEG-HEMA，將其溶於氯仿內，並且成功的製作出支架。然而PEG-HEMA在氯仿內的溶解效果是需要改善的，除此之外舊系統無法製作出多於五層的多孔性支架，因此在此篇研究中，PEG-HEMA的合成與系統的改善，並且製作出層厚較厚且較精準的3D支架。
在PEG-HEMA的合成中，使用98%的HEMA來取代96%的HEMA，此PEG-HEMA不僅僅是在氯仿下可以完全的溶解並且也在其他的溶劑有相當好的溶解效果，例如丙酮，因此PEG-HEMA 以及 PCL-PEG-PCL二次溶解的問題也將一併被改善。此外，系統的架構被改善得更加穩定。以DLP數位光學鏡頭投射器直接取代動態光罩產生器，因此新的系統能有效改善光罩圖形及成型效果。
在3D多孔性支架製作方面，所達到的層數與結果都已較舊系統的佳，但由於前一層已固化的支架所造成光反射的現象，導致支架有過度固化以及在堆疊六層後支架孔洞產生封閉的情況。為此使用三種方法來嘗試解決這個問題—減少每層的固化時間、利用遞減支架來補償支架放大的影響以及使用組合式支架的方式。從結果來看，組合式支架的製作方式能夠縮小支架尺寸誤差，以六層支架來說，其誤差可從40%縮小到5.6%。利用組合式的方法，可能製作出多層且精確的3D支架，並且沒有孔洞封閉的問題。

In the previous Dynamic Mask Rapid Prototyping System developed in our laboratory, PCL-PEG-PCL was mixed with PEG-HEMA in chloroform and cured to create scaffolds successfully. However, the solubility of PEG-HEMA in chloroform is still an issue to be improved. Besides, the old system could not create scaffolds more than 5 layers without pore closure. Therefore, in this research, PEG-HEMA synthesis and the system were improved. Moreover, thicker and more precise 3D scaffolds were fabricated.
In PEG-HEMA synthesis, 98% HEMA was used to replace 96% HEMA. The new PEG-HEMA can be dissolved completely in not only chloroform but also other solvents, such as acetone. The re-dissolution issue of PEG-HEAM and cured PCL-PEG-PCL was also improved. Besides, the structure of the system was redesigned to provide stability and a DLP projector was adopted directly to replace the assembled dynamic mask generator. The new system was capable of providing better mask images and performance.
In 3D porous scaffold fabrication, the achievable layers and results were better than the old system, but due to the reflection of previous cured layers, over-cure happened and pores may be closed after 6 layers. Three approaches were tested to solve this problem—decreasing the curing time of later layers, decreasing the scaffold dimensions of later layers for compensation, and assembling basic scaffold sets. As a result, assembling basic scaffold sets was the best among three and could reduce the scaffold dimension error effectively from 40% to 5.6% for a 6-layer scaffold. With this assembly strategy, it is possible to fabricated thick and precise 3D scaffolds without pose closure problem.

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