先前實驗室所發展的動態光罩快速成型系統中，使用PCL材料加上光交聯劑PEG-HEMA來作為生醫材料系統，因PEG-HEMA製備時間過於冗長，故本研究將探討否可以有效縮短生醫材料製備時間；本研究亦會將整體系統做改善，縮短整體製程時間更快速以及提升支架精度。
本研究採用聚己內酯(PCL)直接與acryloyl chloride做合成，此生醫材料合成時間為三小時，合成後的材料不需再添加PEG-HEMA即可受光激發交聯，因此在製備時間做了有效的縮短在實驗的過程中發現本材料所製成的支架為透明無色，一併解決先前材料為乳白色，會造成已固化材料相互反射而造成精度上的誤差與孔洞無法衝出等問題。此外，用原本系統照射於本研究的材料上會有照射時間過久的問題，故將取下先前實驗的鏡頭套統直接投射，提升光強度，讓原本單層製作時間30秒縮短為15秒，可縮短支架製作時間，並利用影像處理二值化計算出每pixel對應的值為20μm，利用鏡頭的變更並使整體縮放比例為1/10，使得支架在設計與製作中取得一個較精確的計算比例，以期可製作更複雜幾何外型之支架。
本研究製作3D管狀結構，分為兩種形式製作：第一是以2D pattern轉一角度或偏移堆疊的方式製作，本實驗利用六邊形、方形以及三角形作為基本圖元來進行製作；另一個是以雙面梯形單元做陣列來設計出3D連通多孔性支架。本研究成功製作出多種3D多孔性連通支架，未來期望應用於組織工程細胞生長，協助細胞複製以及達到修復人體器官之目的。

In the previous Dynamic Mask Rapid Prototyping System developed in our laboratory, PCL mixed with PEG-HEMA were used as the bio-medical material system. In this previous system, however, the PEG-HEMA preparation is a time –consuming process. This study is devoted to decreasing the preparation time of bio-material, as well as improving the system, decreasing the whole process time, and raising the scaffold accuracy.
In this study, the bio-medical material is synthesized using PCL and acryloyl chloride for three hours. The synthesized material can be photoinitiated cross-linking without adding PEG-HEMA, indicating that the preparation time of bio-medical material is decreased effectively. In addition, the scaffold fabricated using the synthesized material is tend to be transparency, improving the problems of fabrication accuracy error and pore closure caused by the reflection of white cured material. The additional problem is the over-irradiating of the synthesized material in this study by using the previous Dynamic Mask Rapid Prototyping System. To address this problem, the visible light source irradiate directly to the material, meaning that the light intensity is increased. With this mechanism, it abridges not only the fabrication time of single layer from 30s. to 15s, but also the total fabrication time of scaffold. Beside, calculating every single pixels which equal to 20 um bythreshold and lessening the volume to first tenth by changing the lens will attain a more specific ratio about the scaffold in the design and the fabrication. Finally, fabricating more complex scaffolds in the geometric type will be more acceptable.
This study presents the fabrication of 3D tube structure of scaffold which can be divided into two types: (1) The 3D scaffolds with interconnected pore network fabricated by angle turning or shifting layer-by-layer with 2D patterns including hexagon, triangle, and square. (2) 3D scaffolds with interconnected pore network: which are fabricated by the array design of double-side trapezoid unit. Various 3D porous scaffolds have been successfully fabricated in this study. In the future, it can be expected to be used in tissue engineering cell growth, mass cell duplication, and human organs repair.

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