本論文使用微擾注入鎖定(perturbation-injection-locked, PIL)技術，發展一種新型非侵入式血糖感測器，透過手指因血糖變化造成的介質改變，放上感測器造成微擾所產生的頻率偏移，經注入振盪器中，使振盪器的頻率偏移。在此微擾注入鎖定感測器裡，使用互補式隙環共振器(CSRR)作為感測器中的感測元件，該感測元件之設計與測試詳述於論文中。再之，為加強感測靈敏度，本論文亦設計自振式互補式隙環共振器，並使用網路分析儀擷取因血糖變化造成之相位斜率變化。此外，整合上述感測元件與自振式共振器，可形成一「微擾注入鎖定感測器」，並應用於觀察受測者飲用含糖飲料前後的手指血糖變化對感測器振盪頻率造成的影響。實驗期間並使用血糖機量測結果作對照，可初步找出頻率變化量與血糖值間的關係。根據實驗結果，發現本感測器分析的頻率變化量測結果與血糖機所量測出的數值，前20分鐘趨勢相同，並於實驗尾聲趨於平緩，目前雖然尚未得到頻率偏移量與血糖機數值間的絕對關係，但由分析結果可觀察出此感測器具有非侵入式感測血糖的潛力。

This thesis develops a new type of non-invasive sensor for blood glucose sensing based on perturbation-injection-locked (PIL) technology. As a finger put upon the resonant-type sensor, it makes a resonant frequency shift based on the perturbation theory. It is because the blood glucose fluctuation of the finger leads to the permittivity variation. The output signal from the oscillator goes through the CSRR sensing component and lead to a phase shift. This phase-modulated signal injects into the oscillator to generate an oscillation frequency deviation. This amount of the oscillation frequency deviation will be employed to relate the blood glucose variation. The design and evaluation of the complementary split-ring resonator (CSRR), which is treated as the sensing component in the PIL sensor, is described in detail in this thesis. Additionally, the self-oscillating CSRR is further designed for improving sensitivity. The results of the transmission phase slopes caused by the blood glucose fluctuations are carried out by the vector network analyzer. Consequentially, by integrating the above-mentioned sensing component, CSRR, and self-oscillating CSRR into a “perturbation-injection-locked sensor”, it can be applied to observe the blood glucose change of the subject under test before and after drinking sugary drinks. The relationship between oscillation frequency deviations and blood glucose levels can be initially obtained by comparing with the measured results of the blood glucose meter in experiment. According to the experimental results, the distribution of the measured oscillation frequency deviations detected by the sensor has the similar trend with the data measured by blood glucose meter during the first 20 minutes. Although the absolute relationship between oscillation frequency deviations and the values measured by the blood glucose meter have not been obtained yet, the sensor developed in thesis experimentally demonstrates the great potential for non-invasive blood glucose sensing.

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