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研究生: 連子逸
Zi-Yi Lian
論文名稱: 可攜式新型瞳孔檢測裝置實作與對人眼之非成像光學模擬分析
Non-imaging Optical Simulation Analysis of Human Eye and Implementation of Portable Innovative Pupillometer
指導教授: 黃忠偉
Jong-Woei Whang
口試委員: 黃忠偉
Jong-Woei Whang
徐巍峰
陳怡永
王孔政
Kung-Jeng Wang
學位類別: 碩士
Master
系所名稱: 電資學院 - 電子工程系
Department of Electronic and Computer Engineering
論文出版年: 2018
畢業學年度: 106
語文別: 中文
論文頁數: 67
中文關鍵詞: 瞳孔計人眼模型影像處理光生物安全光學模擬
外文關鍵詞: Pupillometer, Eye Model, Image Processing, Photobiological Safety, Optical Simulation
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  • 瞳孔大小的測量對於了解病人的即時的生理狀況相當重要。這項量測已經被
    急診室醫務人員所採用。瞳孔大小的記錄在急診室,神經科室和其他外科診斷為被
    視為必要的信息。雖然使用了一些更複雜的瞳孔計,但它們昂貴而且移動性較差。
    在這項研究中,我們開發了一種新型手持式瞳孔計,其特色為低成本,方便攜帶,
    操作簡單。
    這項研究開發的設備,將提供現有的醫務人員在面對病患時進行第一步的狀
    態評估,其可快速確定瞳孔大小,並可為醫務人員提供準確的定量值,這將增強第
    一線醫務人員和護士在未來的便利性。光源使用到一刺激光源,及紅外線發射器,
    以達到刺激瞳孔及增加眼睛成像的品質,在光源與虹膜抓取演算法下的使用下,能
    夠成功辨識瞳孔後將顯示的數值顯示於螢幕上,以提供醫務人員瞳孔大小的實際
    數值。針對光源對人眼的影響,我們通過非序列式光學模擬,進行眼球與偵測裝置
    光源的,眼睛模型將使用Navarro 等人提出一個四階非球面結構的模型,評估光源
    可對人眼進行刺激且通過光生物安全驗證,用於影像處理時可提高其對比度,結果
    證明該裝置的硬體設備對於人眼瞳孔得偵測可達到預期的效果。


    The pupil size measurement is very important for understanding the patient's
    immediate physiological condition. This measurement has been addeopted by medical
    staff in the emergency room. The pupil size is recorded in the emergency room, neurology
    room and other surgical diagnoses as necessary information. Although some more
    complex pupillometers are used, they are expensive and less mobile. In this study, we
    developed a portable innovative pupillometer featuring low cost, easy portability, and
    simple operation.
    The research and development of the equipment will provide an assessment of the
    status of the first steps of the existing medical staff in the face of the patient. It can quickly
    determine the pupil size and provide accurate quantitative values for the medical staff.
    This will enhance the convenience of the first medical staff and nurses in the future. The
    light source uses a stimulating light source and an infrared emitter to stimulate the pupil
    and increase the quality of eye imaging. Under the use of the light source and iris capture
    algorithm, the pupil value can be displayed on the screen after successfully identifying
    the pupil. To provide the actual value of medical personnel pupil size. For the effect of
    the light source on the human eye, we use non-sequential optical simulations to perform
    eyeballs and light sources for the pupillometers. The eyeball model will use Navarro et
    al. to propose a fourth-order aspheric structure model [1] to evaluate the light source. The
    human eye performs stimuli and passes photobiological safety verification, which can
    improve the contrast when used in image processing. The result proves that the hardware
    of the equipment has the expected effect on the detection of the pupil of the human eye.

    目次 中文摘要 ii ABSTRACT iii 致謝 iv 目次 v 圖次 vii 表次 x 第一章 緒論 1 1.1 研究背景 1 1.2 研究動機與目的 2 1.3 論文架構 3 第二章 光學基礎與光生物安全 4 2.1 光度學單位簡介 4 2.1.1 光通量 ( Luminous Flux, Φ ) 5 2.1.2 光強度 ( Luminous Intensity, I ) 6 2.1.3 光強度 ( Luminous Intensity, I ) 6 2.1.4照度 ( Illuminance, E ) 7 2.1.5輝度 ( Luminance, L ) 9 2.2 光生物安全 10 2.2.1 危害暴露限制 10 2.2.2 生物學效應 12 第三章 眼科學基礎 14 3.1 人眼 14 3.1.1 眼的組織解剖與生理 14 3.1.2 眼神經 16 3.1.3 視網膜生理 17 3.2 瞳孔檢查 18 3.2.1 虹膜反射 18 3.2.2 相對性傳入性瞳孔反應 19 第四章 瞳孔檢測儀器介紹 20 4.1 現有瞳孔檢測儀器公司 20 4.2 儀器檢測功能與操作 21 第五章 設計概念與模擬方法 23 5.1硬體設計 23 5.2 測距模組與相機 26 5.3 設備操作程序 30 5.4 影像處理與瞳孔辨識 31 5.5人眼模型建立與光生物安全模擬 38 5.5.1人眼模型與暴露限制 38 5.5.2 人眼相機影像之光學模擬 40 第六章 測量結果與模擬分析 41 6.1 相機影像結果 41 6.2 瞳孔量測結果分析 43 6.2.1 測距感應測試結果 43 6.2.2 瞳孔抓取程式測試結果 43 6.2.3 實際量測瞳孔變化結果 45 6.2.4 瞳孔量測可靠度測試 47 6.3 光生物安全模擬分析 48 6.3.1 眼球入射光線追跡模擬 48 6.3.2暴露限制結果 50 第七章 結論與未來展望 51 7.1 結論 51 7.2 未來展望 52 參考文獻 53

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