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研究生: 胡登傑
deng-jie Hu
論文名稱: 智慧型自動辨識及計算下鼻甲及上頷竇體積於電腦斷層影像之系統
Intelligent and Automatic Computed Tomography System of Inferior Turbinate and Maxillary Sinus Volume Identification and Calculation
指導教授: 郭中豐
Chung-Feng Jeffrey Kuo
口試委員: 朱永祥
Yueng-Hsiang Chu
呂宜興
Yi-Shing Leu
蘇德利
Te-Li Su
蔡鴻文
Hon-Wen Tsai
學位類別: 碩士
Master
系所名稱: 工程學院 - 材料科學與工程系
Department of Materials Science and Engineering
論文出版年: 2013
畢業學年度: 101
語文別: 中文
論文頁數: 122
中文關鍵詞: 影像處理參數化模板倒傳遞類神經網路等位函數法
外文關鍵詞: Image processing, Parametric Template, Back Propagation Neural Network, Level Set
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醫學領域中,可藉由許多方式檢視人體內部的構造及器官,如早期的X光片,隨後發展電腦斷層影像(Computed Tomography, CT)、核磁共振造影(Magnetic Resonance Image, MRI)、微斷層攝影(Microtomography)等各種可用於顯示各種不同部位組織構造或是病徵的影像,以輔助醫生診斷病因。本研究運用影像處理技術自動辨識下鼻甲(Inferior turbinate, IT)及上頷竇(Maxilary Sinus, MS),擷取電腦斷層影像訊號後先對影像做灰階處理後,將其正規化並針對下鼻甲及上颔竇區域(Region of Interesting, ROI)利用參數化模板匹配(Parametric Template, PT)擷取相似度特徵值,再對下鼻甲區域(Sub Region, SR)計算波形特徵值,再透過倒傳遞類神經網路(Back Propagation Neural Network, BPNN)訓練網路資料庫以判斷是否有ROI存在,判斷為是則再接著使用等位函數法(Level Set)將下鼻甲及上頷竇輪廓框圈選出來,再透過迴歸方程擬合出體積。本研究所開發之智慧型自動辨識及計算下鼻甲與上頷竇體積於電腦斷層影像之系統與醫師圈選之結果驗證得到之系統信賴度(Kappa)為0.86、整體準確率(Accuracy)為97.92%,確實可輔助醫師診斷下鼻甲及上頷竇之病情。


In the medical field, there are many methods to examine the internal structures and organs of human body, such as X-ray, computed tomography (CT), magnetic resonance image (MRI), and microtomography (micro-CT), which can display different parts of the tissues or symptoms, to assist in diagnosis. This study used the image processing technology to automatically identify the inferior turbinate and maxillary sinus. After capturing the computed tomography signals, the grey level processing was performed on the image. The image was normalized, and the parametric template matching was used to capture the similarity eigenvalues specific to the inferior turbinate and maxillary sinus areas. The waveform eigenvalues of the inferior turbinate area were calculated, and entered into the back-propagation neural network (BPNN) training network database in order to determine whether there ROI exists. If yes, the level set method is used to circle the contour box of the inferior turbinate and maxillary sinus, and the volume was fit by the regression equation. According to the verification of the results of the intelligent and automatic CT system of inferior turbinate and maxillary sinus volume identification and calculation, in comparison to the areas circled by the physicians, the system reliability reached 0.86 and the overall accuracy rate was 97.92%. The proposed system is proven to be able to assist physicians in diagnosing the state of illness of inferior turbinate and maxillary sinus.

摘要 I ABSTRACT II 致謝 III 目錄 IV 圖目錄 VII 表目錄 XI 第1章 緒論 1 1.1 研究背景與動機 1 1.2 文獻回顧 4 1.3 論文架構 9 第2章 影像擷取系統與影像處理軟體 11 2.1 影像擷取系統 11 2.2 電腦硬體設備與作業系統 13 2.3 影像處理軟體 13 第3章 相關醫學簡介 14 3.1 鼻竇 14 3.2 鼻甲構造 17 第4章 研究方法及相關理論 18 4.1 影像空間 18 4.2 正交投影 19 4.3 影像分割 21 4.4 形態學 27 4.5 參數化模板匹配 31 4.6 倒傳遞類神經網路 36 4.7 等位函數法 46 4.8 醫學診斷試驗 52 第5章 實驗與結果與分析 54 5.1 模板擷取 55 5.2 影像特徵值擷取 56 5.3 倒傳遞類神經網路 63 5.4 等位函數法 68 5.5 三維重建與體積計算 81 第6章 結論 88 參考文獻 90 附錄一 96 附錄二 107

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