本文提出一主動袖套壓力控制血壓計，其採用共振法進行血壓之量測。相較於傳統袖套式電子血壓計量測方法，本研究最大特色在於使用可變體積壓力艙，並透過改變壓力艙之體積來達成量測血壓時之袖套壓力調整目的。此一可變體積壓力艙之運作係由馬達驅動線性螺桿來改變單動式氣壓缸內活塞之位置，並實現閉回路壓力控制方法；其大幅消弭了傳統袖套式電子血壓計在氣壓幫浦加壓時之氣體擾流與噪音。此一主動袖套壓力控制血壓計可於加壓過程即時量得血壓值，並能於量測到收縮壓後快速抽回袖套內之空氣，大幅降低量測時間與不舒適感。此外，此一方法亦可自動規劃非線性之加壓與減壓曲線，以同時兼顧到量測時間與解析度，並能藉由持續性多次的加壓與減壓過程來增加血壓值的量測準確度。因此可應用於加護病房之非侵入式長時間血壓監控用途。本研究亦以Android嵌入式系統開發監控人機介面，以支援未來手持式健康監控系統之相關應用。最後，本研究以共振法原理之市售血壓計（Microlife BP2BO0）進行量測重現性比較。在同一使用者連續十次之量測下，實驗結果顯示市售血壓計收縮壓量測標準差為4.17、舒張壓量測標準差為3.64。而本研究之血壓計量測收縮壓之標準差為3.72，舒張壓之標準差為3.25，因此，量測重現性比市售共振法血壓計高；此外，量測時間上也比市售血壓計平均快上6秒（16%）。

This study proposes a cuff oscillometry blood pressure (BP) measurement approach based on active cuff pressure control schemes (ACPCS). The most important feature of the proposed ACPCS-based BP measurement approach is the use of variable volume pressure chamber (VVPC) technology for altering the cuff pressure when compared to conventional electronic cuff BP instruments. The VVPC is operated with a closed-loop pressure control scheme, and it is activated in terms of altering the piston position of a single-acting cylinder that is driven by a motor with a linear screw. Therefore, the VVPC significantly eliminates the disturbance and noise at the injecting air stage of using a conventional BP pump. More importantly, the ACPCS-based BP measurement approach is capable of obtaining the BP at the air injection stage, and the air in the cuff can be fast extracted to the VVPC when the systolic blood pressure (SBP) is detected. In this manner, the ACPCS-based BP measurement approach may benefit the measurement time and user comfort. At the same time, nonlinear pressure courses for injecting and extracting air are also automatically generated to achieve the considerations of both measurement time and resolution. Moreover, continuous and repetitive injecting and extracting courses are desirable for improving the measurement accuracy. Hence, such a BP solution is applicable for invasive long-term BP monitoring in intensive care units. A graphical-user-interface (GUI) is developed with an Android-based embedded platform, and it can be used for future hand-held healthcare applications. Finally, a cuff-oscillometry-based commercial BP instrument (Microlife BP2BO0) is used for the performance comparison of measurement repeatability. Based on ten times continuous measurements of a subject, the measurements of standard deviations of systolic and diastolic pressures of the commercial BP instrument are 4.17 and 3.64, respectively. The systolic and diastolic pressures of the proposed BP instrument are 3.72 and 3.25, respectively. The experiment results demonstrated that the proposed BP instrument performs better measurement repeatability. Moreover, the measurement time could reduce 6 seconds (i.e., 16%) when compared to the examined commercial BP instrument.

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