本研究為評估菱角殼纖維(CSF)與聚羥基烷酸酯(PHA)複合材(PHA/CSF)以及CSF與PHA接枝甲基丙烯酸縮水甘油脂(PHA-g-GMA)複合材(PHA-g-GMA/CSF)之機械性質、生物相容性與生物降解性。
研究發現PHA-g-GMA/CSF相較於PHA/CSF有較好的機械性質，CSF在縮合反應時可以均勻的分散在PHA-g-GMA的基質中；將人包皮成纖維細胞(HFF)附著於這兩種複合材上以測生物相容性；附著於PHA/CSF複合材上FBs之細胞增生率與產生的膠原蛋白皆較PHA-g-GMA/CSF複合材為佳；PHA-g-GMA/CSF複合材比PHA/CSF有較好的抗水性；將兩種複合材放入放射性根瘤菌(Rhizobium radiobacter)中皆有重量的損失，及指出兩種複合材皆有生物降解性，且生物降解性會隨CSF濃度上升而升高，另PHA/CSF與PHA-g-GMA/CSF複合材之生物降解性皆比純的PHA好。

The mechanical properties, biocompatibility and biodegradability of composite materials made from chestnut shell fibre (CSF) and poly(hydroxyalkanoate) (PHA), as well as CSF and glycidyl methacrylate grafted PHA (PHA-g-GMA), were evaluated. Composites formed from PHA-g-GMA/CSF were found to have noticeably superior mechanical properties compared with those of PHA/CSF. CSF could be homogeneously dispersed in the PHA-g-GMA matrix as a result of condensation reactions. Human foreskin fibroblasts (FBs) were seeded on these two series of composites to characterise the biocompatibility properties. FB proliferation and collagen production on the PHA/CSF series of composites were superior to that on the PHA-g-GMA/CSF composites. PHA-g-GMA/CSF was found to be more water resistant than PHA/CSF, although the weight loss of both composites buried in Rhizobium radiobacter compost indicated that both were biodegradable, especially at high levels of CSF substitution. Furthermore, the PHA/CSF and PHA-g-GMA/CSF composites were more biodegradable than pure PHA.

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