近幾年氣球擴張術和支架放置術已是治療冠狀動脈嚴重阻塞和狹窄的主要方式之一。血管支架放置術為利用心導管將血管支架送入冠狀動脈內，將狹窄或阻塞的部位撐開，以增加冠狀動脈的血流量。316L不鏽鋼為氣球擴張型支架的主要選用材料之一，其優點為生物相容性較高、有適當的強度和彈性、能抗疲勞及具有良好加工成形性等。
本研究針對以光纖雷射加工的316L不鏽鋼生醫心血管支架，開發其後處理製程。研究中以新的漿體噴射研磨(slurry jet grinding) 技術取代傳統的噴砂技術對雷射加工後支架進行研磨，之後使用酸洗和電解拋光技術對支架進行表面平整化和拋光處理。漿體噴射研磨研究探討了研磨漿體衝擊角度、氣壓大小、漿體黏滯係數和流速對加工後支架表面的影響，除此之外在本研究中，利用商用CFD (computational fluid dynamics)軟體以有限體積法(finite volume method, FVM)，模擬於漿體噴射研磨中不鏽鋼支架在不同外管徑下之加工行為特徵。酸洗處理部分主要探討酸洗時間對支架表面的影響。電解拋光研究主要探討電壓、時間、重量移除百分比等操作參數之最佳化，以達到支架表面有最佳的亮度，並去除原始尖銳邊緣使支架邊緣圓角化，以避免使用支架進行治療時可能造成器官非期望性的損傷。完成後的血管支架直徑2mm長度20mm並置入氣球導管上，以測試其可壓縮和擴張性。

Angioplasty and stent placement surgery have become the major treatment for coronary artery occlusion and severe stenosis. Stent placement surgery uses cardiac catheter to place a metal stent into the coronary stent and expand it to deal with the stenosis or obstruction of the distraction site to increase coronary blood flow. The most common material used for balloon-dilatation stent is 316L stainless steel. 316L stainless steel has high biocompatibility, sufficient strength and toughness, suitable hardness and elasticity, fatigue resistance and good formability in manufacturing process.
In this study, experiments were performed to optimize the post treatment processes, including slurry jet grinding (SJG), acid pickling and electro-polishing, for laser cutting stainless steel cardiovascular stents. Slurry jet grinding is a new method to grind the laser cutting stents, instead of conventional sand blasting. Experiments were proceeded to study the effect of particle impingement angle, air pressure, slurry viscosity and fluid velocity on the grinded stent profile and surface quality. In addition, a commercial computational fluid dynamics (CFD) software based on the finite volume method (FVM) was used for simulating the outer tube diameter effect on the process behaviors and characteristics in slurry jet grinding. The simulation results were compared with experiments. In the study of acid pickling time influence on stent surface characteristics is focused. Several electro-polishing parameters, including applied voltage, time and total removed weight percentage, were investigated in this work to optimize the electro-polishing process for achieving better surface roughness and edge rounding. Finally, the fabricated cardiovascular stents, with diameter 2 mm and length 20 mm, were crimped into a catheter to investigate their compressibility and expandability.

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