目前對於口腔及顱顏面受到創傷的病患，常因為無法有效評估骨折移位，檢查咬合狀態，並取其牙模重建評估，使得在整個醫療處理過程受到侷限，並影響到病患後續的復原。又因牙齒的咬合狀態需精準配合，顎骨模型的精度於臨床應用上有嚴格之要求。因此，本研究利用電腦斷層掃描，搭配影像處理和快速成型技術，基於不二次傷害病患口腔及顱顏面組織的情況下，製作出病患完整的上下顎骨模型，以供術前規劃模擬之用。
本研究首先建立顱顎生物模型的一般製作流程，將電腦斷層掃描影像，透過商用醫學影像處理軟體，轉成CAD檔案，再使用快速成型技術製作出顎骨模型。與實體比對，發現誤差量約在1~2mm，未能達到臨床應用1mm以下之需求。透過誤差來源的分析，針對流程中可能的誤差如CT層厚差距、影像閥值選取與編輯、RP模型製作等，加以探討改善，進而訂定一套新的標準流程，製作出精度較高的實體模型，平均誤差可降至0.25mm。此外，亦將此標準流程應用於8個實際病例，平均誤差在0.3mm以下，證實可成功代替牙模型之使用。本研究所產生的高精度生物模型，將有助於提高手術成功率及安全性，降低手術後併發症及節省治療時間與醫療成本，為口腔顎面創傷的病患，提供新的醫療選擇，亦可推廣於其他類似的應用。

Most oral and craniofacial trauma patients cannot have their fracture displacement assessed effectively, neither can they examine their occlusion nor re-evaluate their dental cast. This restricts the whole medical process and influences the recovery of the patients. Besides, occlusion requires accurate functional contact, thus the accuracy of the maxillofacial model needs to meet strict clinical demands. Therefore, in this research, we attempt to get the complete maxillofacial model of patients without damaging the oral and craniofacial tissues of patients by using computed tomography (CT) along with image processing and rapid prototyping (RP) technique.
At first, a set of procedures of generating maxillofacial model was developed. CT images were segmated and converted to a CAD file by a commercial mdeical image processing software. RP technique was used to fabricate maxillofacial model. After comparison, the deviations were around 1-2mm, which did not meet clinical demands of less than 1 mm. After analying the sources errors, issues of CT slice thickness, image’s throushold selection and editing, and RP fabrication were investigated to improve the accuracy. As a result, new standard procedures were suggested to obtain RP maxillofacial models with higher accuracy. The improved average deviation can be reduced to 0.25mm. Furthermore, the new procedures were applied to 8 actual cases, and the average error was less than 0.3mm. This proves the RP maxillofacial models can replace the role of dental cast. The biological RP models with high accuracy generated in this research can improve sucess rate and safety in a surgery. It can also reduce complications after the surgery, as well as the time of treatment and medical cost. It provides the oral and maxillofacial trauma patients a new medical option, and can be applied to other similar applications.

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