本研究分別利用切削加工及脫蠟澆注法製作出PMMA與PDMS冠狀動脈瘤流場可視化之模型，並藉由改變不同的加工製作參數，分析參數對於模型品質的影響，進而找出對於製作模型而言最佳的加工參數組合，改善模型品質。在壓克力的切削性實驗部分，以進給率250 mm/min和0.5 mm的刀層切深可得到最佳的表面粗糙度。在PMMA模型的製作中，利用三軸加工與五軸加工製作出流場可視化模型，結果顯示利用五軸加工可減少模型在製作時因刀具軸向限制而需分解過多工件與加工面進行加工的缺點。而在PDMS脫蠟澆注蠟模參數實驗的部分，以3 Psi的射出壓力與100 ℃的射出溫度可得到最佳的蠟模品質。而在蠟模脫蠟的部分，以熱水脫蠟且水溫在80-90 ℃可使PDMS減少變質的現象，得到最佳的PDMS模型品質。

In this thesis, we study on the manufacturing process of coronary aneurysm flow field visualization models. Both PMMA and PDMS were utilized to produce the model. These two materials were processed by cutting and lost-wax casting, respectively. Different manufacturing parameters were studied to find the best combination of processing parameters in the experiment. In PMMA machinability test, the feed of 250 mm/min and the depth of cut of 0.5 mm can get optimal surface roughness. In addition, the results show that 5-axis milling can reduce the number of the parts caused by 3-axis milling tool constraints. In PDMS lost-wax casting experimental tests, with 3 Psi injection pressure and 100 ℃ injection temperature can get the best quality of wax model. In dewaxing process, by using 80-90 ℃ hot water to dewax the model can avoid the deteriorate of PDMS model and keep the transparency of PDMS model.

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