高通量微流體裝置(High throughput Microfluidic Device)在處理大量樣品的分子生物學中，顯著地加速了整個生化反應過程，是一個強大的工具。本研究的目的是利用氣動式系統驅動高通量微流體裝置中的液滴移動及定位。為了達到這個目的，製作單一流道的微結構來了解如何在液氣二相流的系統中精確地控制液滴。利用微铣削(Micro Milling)和熱黏合(Thermal Bonding)的方式製造高分子微流體晶片。開發LabVIEW程式控制連接至微流體裝置的氣壓系統。實驗結果顯示，在微流道表面上塗佈疏水塗層，氣壓驅動下，液滴在微流道中來回移動重覆40次明顯地減少了損失，僅僅6.9%的損失率。

High throughput microfluidic device is a powerful tool in processing multiple samples in molecular biology and significantly accelerate the overall biochemical process.The aim of this research is to use a pneumatic system to drive multiple droplets move and position in a highthroughput microfluidic device.To achieve this purpose,a single microchannel device is fabricated to understand how to precisely control a single droplet in a gas-liquid two phase flow system.The polymer microfluidic device is manufacture with micromilling and thermal bonding.A home-made pneumatic system controlled by LabVIEW is developed is connected to the microfluidic device.A hydrophobic coating is realized on the surface of micro channel to minimize the reagent loss during the repeatedly flowing cycles.The experiment results show that the pressure-driven droplet can move the microchannel repeatedly for 40 times with a reagent loss of 6.9%.

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