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研究生: 陳柏彰
Bo-Jhang Chen
論文名稱: 碳量子點之製備及其光動力與抗氧化之應用
Synthesis of carbon quantum dots and their applications to photodynamic and anti-oxidation
指導教授: 張家耀
Jia-Yaw Chang
口試委員: 蔡伸隆
Shen-Long Tsai
黃志清
Chih-Ching Huang
學位類別: 碩士
Master
系所名稱: 工程學院 - 化學工程系
Department of Chemical Engineering
論文出版年: 2022
畢業學年度: 110
語文別: 中文
論文頁數: 126
中文關鍵詞: 碳量子點光動力抗氧化
外文關鍵詞: carbon quantum dots, photodynamic, anti-oxidation
相關次數: 點閱:312下載:0
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摘要 I Abstract III 致謝 V 總目錄 VI 圖目錄 IX 表目錄 XVI 第一章、緒論 1 1.1 前言 1 1.2 研究動機與目的 3 第二章、理論基礎及文獻回顧 5 2.1 碳量子點(Carbon Quantum Dots,CQDs) 5 2.1.1 碳量子點之起源 5 2.1.2 碳量子點之光學性質 6 2.1.3 碳量子點之發光機制 10 2.2 碳量子點之合成與發展 15 2.2.1 碳量子點之合成方式 15 2.2.2 無機酸輔助碳量子點之表面修飾 26 2.2.3 異原子摻雜之碳量子點 31 第三章、實驗儀器與方法 38 3.1 實驗藥品 38 3.2 實驗儀器 41 3.3 實驗步驟 44 3.3.1 紅色螢光碳量子點之合成(Synthesis of CDs) 44 3.3.2 酸處理紅色螢光碳量子點之合成(Synthesis of acid-treated CDs) 44 3.3.3 過氯酸處理紅色螢光碳量子點之最適化合成(Synthesis of HClO4-CDs) 45 3.3.4 硫原子摻雜紅色螢光碳量子點之合成(S-CDs) 45 3.4 光動力檢測方法 45 3.4.1 生成單態氧能力檢測 45 3.4.2 生成•OH自由基能力檢測 46 3.4.3 生成O2-•自由基能力檢測 47 3.5 抗氧化活性檢測方法 48 3.5.1 清除DPPH自由基能力檢測 48 3.5.2 清除•OH自由基能力檢測 48 3.5.3 清除O2-•自由基能力檢測 49 3.6 細胞培養與細胞實驗 50 3.6.1培養液(medium)與磷酸鹽緩衝液(PBS)之配製 50 3.6.2解凍細胞(Cells Defrost) 51 3.6.3繼代培養(Cell Culture) 51 3.6.4細胞計數(Cell Counting) 52 3.6.5冷凍細胞(Cell Cryopreservation) 53 3.6.6 CDs、HClO4-CDs、S-CDs於細胞體外之材料毒性測試 53 3.6.7 CDs、HClO4-CDs、S-CDs於細胞體外之光動力治療 54 3.6.8 CDs、HClO4-CDs、S-CDs於細胞之螢光顯影試片製作 55 第四章、結果與討論 57 4.1 過氯酸處理與硫原子摻雜紅色螢光碳量子點之合成(CDs、HClO4-CDs、S-CDs) 57 4.1.1 CDs、HClO4-CDs、S-CDs之實驗介紹 57 4.1.2 CDs處理不同酸性試劑條件之探討 58 4.1.3 HClO4-CDs於不同HClO4濃度之最適化條件探討 60 4.1.4 S-CDs於摻雜不同S原子濃度之最適化條件探討 62 4.1.5 CDs、HClO4-CDs、S-CDs之材料鑑定與分析 63 4.2 CDs、HClO4-CDs、S-CDs之光動力與抗氧化活性分析 72 4.2.1 CDs、HClO4-CDs、S-CDs之光動力分析 72 4.2.2 CDs、HClO4-CDs、S-CDs之抗氧化活性分析 80 4.3 CDs、HClO4-CDs、S-CDs之體外細胞治療應用 87 4.3.1 CDs、HClO4-CDs、S-CDs之體外細胞毒性測試 87 4.3.2 CDs、HClO4-CDs、S-CDs於體外細胞之光動力療法應用 88 4.3.3 CDs、HClO4-CDs、S-CDs於體外細胞之生物顯影應用 88 第五章、結果與未來展望 96 參考文獻 97

[1] W. Cai et al., "Full color carbon dots through surface engineering for constructing white light-emitting diodes," Journal of Materials Chemistry C, 10.1039/C9TC00274J vol. 7, no. 8, pp. 2212-8, Jan 30 2019.
[2] H. Li, Z. Kang, Y. Liu, and S.-T. Lee, "Carbon nanodots: synthesis, properties and applications," Journal of Materials Chemistry, 10.1039/C2JM34690G vol. 22, no. 46, pp. 24230-53,Aug 29 2012.
[3] S. R. Kamali, C.-N. Chen, D. C. Agrawal, and T.-H. Wei, "Sulfur-doped carbon dots synthesis under microwave irradiation as turn-off fluorescent sensor for Cr(III)," Journal of Analytical Science and Technology, vol. 12, no. 1, pp. 48-58, Oct 26 2021.
[4] H. Ehtesabi, Z. Hallaji, S. Najafi Nobar, and Z. Bagheri, "Carbon dots with pH-responsive fluorescence: a review on synthesis and cell biological applications," Mikrochim Acta, vol. 187, no. 2, pp. 150-67, Jan 27 2020.
[5] Q. Xu et al., "Heteroatom-doped carbon dots: synthesis, characterization, properties, photoluminescence mechanism and biological applications," J Mater Chem B, vol. 4, no. 45, pp. 7204-19, Dec 7 2016.
[6] X. Xu et al., "Electrophoretic analysis and purification of fluorescent single-walled carbon nanotube fragments," J Am Chem Soc, vol. 126, no. 40, pp. 12736-7, Oct 13 2004.
[7] Y. P. Sun et al., "Quantum-sized carbon dots for bright and colorful photoluminescence," J Am Chem Soc, vol. 128, no. 24, pp. 7756-7, Jun 21 2006.
[8] S. N. Baker and G. A. Baker, "Luminescent carbon nanodots: emergent nanolights," Angew Chem Int Ed Engl, vol. 49, no. 38, pp. 6726-44, Sep 10 2010.
[9] B. De and N. Karak, "A green and facile approach for the synthesis of water soluble fluorescent carbon dots from banana juice," RSC Advances, vol. 3, no. 22-6, p. 8286-90,Mar 22 2013.
[10] S. Zhu, Y. Song, X. Zhao, J. Shao, J. Zhang, and B. Yang, "The photoluminescence mechanism in carbon dots (graphene quantum dots, carbon nanodots, and polymer dots): current state and future perspective," Nano Research, vol. 8, no. 2, pp. 355-81, Feb 01 2015.
[11] P. Li et al., "Luminescent properties of a water-soluble conjugated polymer incorporating graphene-oxide quantum dots," Chemphyschem, vol. 16, no. 6, pp. 1258-62, Apr 27 2015.
[12] Y. Park, J. Yoo, B. Lim, W. Kwon, and S. W. Rhee, "Improving the functionality of carbon nanodots: doping and surface functionalization," Journal of Materials Chemistry A, 10.1039/C6TA04813G vol. 4, no. 30, pp. 11582-603, Jun 27 2016.
[13] J. Ke, X. Li, Q. Zhao, B. Liu, S. Liu, and S. Wang, "Upconversion carbon quantum dots as visible light responsive component for efficient enhancement of photocatalytic performance," Journal of Colloid and Interface Science, vol. 496, pp. 425-33, Jun 15 2017.
[14] J. Zhou et al., "An electrochemical avenue to blue luminescent nanocrystals from multiwalled carbon nanotubes (MWCNTs)," J Am Chem Soc, vol. 129, no. 4, pp. 744-5, Jan 31 2007.
[15] H. Peng and J. Travas-Sejdic, "Simple Aqueous Solution Route to Luminescent Carbogenic Dots from Carbohydrates," Chemistry of Materials, vol. 21, no. 23, pp. 5563-5, Dec 08 2009.
[16] S. Mitra, S. Chandra, S. H. Pathan, N. Sikdar, P. Pramanik, and A. Goswami, "Room temperature and solvothermal green synthesis of self passivated carbon quantum dots," RSC Advances, 10.1039/C2RA23085B vol. 3, no. 10, pp. 3189-93,Jan 07 2013.
[17] H. Li et al., "Water-soluble fluorescent carbon quantum dots and photocatalyst design," Angew Chem Int Ed Engl, vol. 49, no. 26, pp. 4430-4, Jun 14 2010.
[18] L. Bao, C. Liu, Z. L. Zhang, and D. W. Pang, "Photoluminescence-tunable carbon nanodots: surface-state energy-gap tuning," Adv Mater, vol. 27, no. 10, pp. 1663-7, Mar 11 2015.
[19] Y. Yang et al., "One-step synthesis of amino-functionalized fluorescent carbon nanoparticles by hydrothermal carbonization of chitosan," Chem Commun (Camb), vol. 48, no. 3, pp. 380-2, Jan 11 2012.
[20] Y. Wang, L. Dong, R. Xiong, and A. Hu, "Practical access to bandgap-like N-doped carbon dots with dual emission unzipped from PAN@PMMA core–shell nanoparticles," Journal of Materials Chemistry C, 10.1039/C3TC30949E vol. 1, no. 46, pp. 7731-5,Aug 30 2013.
[21] Y. Zhuo, H. Miao, D. Zhong, S. Zhu, and X. Yang, "One-step synthesis of high quantum-yield and excitation-independent emission carbon dots for cell imaging," Materials Letters, vol. 139, pp. 197-200, Jan 15 2015.
[22] H. Liu, T. Ye, and C. Mao, "Fluorescent carbon nanoparticles derived from candle soot," Angew Chem Int Ed Engl, vol. 46, no. 34, pp. 6473-5, Jan 27 2007.
[23] R. Liu, D. Wu, S. Liu, K. Koynov, W. Knoll, and Q. Li, "An aqueous route to multicolor photoluminescent carbon dots using silica spheres as carriers," Angew Chem Int Ed Engl, vol. 48, no. 25, pp. 4598-601, Jun 08 2009.
[24] X. Jia, J. Li, and E. Wang, "One-pot green synthesis of optically pH-sensitive carbon dots with upconversion luminescence," Nanoscale, vol. 4, no. 18, pp. 5572-5, Sep 21 2012.
[25] W. Zhao, C. Song, and P. E. Pehrsson, "Water-soluble and optically pH-sensitive single-walled carbon nanotubes from surface modification," J Am Chem Soc, vol. 124, no. 42, pp. 12418-9, Oct 23 2002.
[26] X. Dong et al., "Fast one-step synthesis of N-doped carbon dots by pyrolyzing ethanolamine," Journal of Materials Chemistry C, 10.1039/C4TC01139B vol. 2, no. 36, pp. 7477-81,Jul 15 2014.
[27] Y. Deng, D. Zhao, X. Chen, F. Wang, H. Song, and D. Shen, "Long lifetime pure organic phosphorescence based on water soluble carbon dots," Chemical Communications, 10.1039/C3CC42600A vol. 49, no. 51, pp. 5751-3,May 09 2013.
[28] M. Tuerhong, Y. Xu, and X.-B. Yin, "Review on Carbon Dots and Their Applications," Chinese Journal of Analytical Chemistry, vol. 45, no. 1, pp. 139-50, Jan01 2017.
[29] M. J. Molaei, "A review on nanostructured carbon quantum dots and their applications in biotechnology, sensors, and chemiluminescence," Talanta, vol. 196, pp. 456-78, May 1 2019.
[30] L. Bao et al., "Electrochemical tuning of luminescent carbon nanodots: from preparation to luminescence mechanism," Adv Mater, vol. 23, no. 48, pp. 5801-6, Dec 22 2011.
[31] X. Li, S. Zhang, S. A. Kulinich, Y. Liu, and H. Zeng, "Engineering surface states of carbon dots to achieve controllable luminescence for solid-luminescent composites and sensitive Be2+ detection," Scientific Reports, vol. 4, no. 1, pp. 4976-83, May 15 2014.
[32] M. J. Krysmann, A. Kelarakis, P. Dallas, and E. P. Giannelis, "Formation mechanism of carbogenic nanoparticles with dual photoluminescence emission," J Am Chem Soc, vol. 134, no. 2, pp. 747-50, Jan 18 2012.
[33] S. Zhu et al., "Highly photoluminescent carbon dots for multicolor patterning, sensors, and bioimaging," Angew Chem Int Ed Engl, vol. 52, no. 14, pp. 3953-7, Apr 2 2013.
[34] S. J. Yu, M. W. Kang, H. C. Chang, K. M. Chen, and Y. C. Yu, "Bright fluorescent nanodiamonds: no photobleaching and low cytotoxicity," J Am Chem Soc, vol. 127, no. 50, pp. 17604-5, Dec 21 2005.
[35] Y. Dong, N. Zhou, X. Lin, J. Lin, Y. Chi, and G. Chen, "Extraction of Electrochemiluminescent Oxidized Carbon Quantum Dots from Activated Carbon," Chemistry of Materials, vol. 22, no. 21, pp. 5895-9, Nov 09 2010.
[36] H. Zheng, Q. Wang, Y. Long, H. Zhang, X. Huang, and R. Zhu, "Enhancing the luminescence of carbon dots with a reduction pathway," Chem Commun (Camb), vol. 47, no. 38, pp. 10650-2, Oct 14 2011.
[37] S. Hu, J. Liu, J. Yang, Y. Wang, and S. Cao, "Laser synthesis and size tailor of carbon quantum dots," Journal of Nanoparticle Research, vol. 13, pp.7247-52,Dec 01 2011.
[38] J. Lu, J. X. Yang, J. Wang, A. Lim, S. Wang, and K. P. Loh, "One-pot synthesis of fluorescent carbon nanoribbons, nanoparticles, and graphene by the exfoliation of graphite in ionic liquids," ACS Nano, vol. 3, no. 8, pp. 2367-75, Aug 25 2009.
[39] M. Liu, Y. Xu, F. Niu, J. J. Gooding, and J. Liu, "Carbon quantum dots directly generated from electrochemical oxidation of graphite electrodes in alkaline alcohols and the applications for specific ferric ion detection and cell imaging," Analyst, vol. 141, no. 9, pp. 2657-64, Apr 25 2016.
[40] Z. Ma et al., "Bioinspired photoelectric conversion system based on carbon-quantum-dot-doped dye-semiconductor complex," ACS Appl Mater Interfaces, vol. 5, no. 11, pp. 5080-4, Jun 12 2013.
[41] D. Tang et al., "Carbon quantum dots enhance the photocatalytic performance of BiVO4 with different exposed facets," Dalton Trans, vol. 42, no. 18, pp. 6285-9, May 14 2013.
[42] J. Deng et al., "Electrochemical synthesis of carbon nanodots directly from alcohols," Chemistry, vol. 20, no. 17, pp. 4993-9, Apr 22 2014.
[43] J. Y. Li et al., "One-Pot Hydrothermal Synthesis of Carbon Dots with Efficient Up- and Down-Converted Photoluminescence for the Sensitive Detection of Morin in a Dual-Readout Assay," Langmuir, vol. 33, no. 4, pp. 1043-50, Jan 31 2017.
[44] X. Cui et al., "Dual functional N- and S-co-doped carbon dots as the sensor for temperature and Fe3+ ions," Sensors and Actuators B: Chemical, vol. 242, pp. 1272-80, Apr 01 2017.
[45] A. B. Bourlinos, A. Stassinopoulos, D. Anglos, R. Zboril, V. Georgakilas, and E. P. Giannelis, "Photoluminescent Carbogenic Dots," Chemistry of Materials, vol. 20, no. 14, pp. 4539-41, Jul 01 2008.
[46] J. Zong, Y. Zhu, X. Yang, J. Shen, and C. Li, "Synthesis of photoluminescent carbogenic dots using mesoporous silica spheres as nanoreactors," Chem Commun (Camb), vol. 47, no. 2, pp. 764-6, Jan 14 2011.
[47] A. de la Hoz, A. Diaz-Ortiz, and A. Moreno, "Microwaves in organic synthesis. Thermal and non-thermal microwave effects," Chem Soc Rev, vol. 34, no. 2, pp. 164-78, Feb 2005.
[48] R. Gedye et al., "The use of microwave ovens for rapid organic synthesis," Tetrahedron Letters, vol. 27, no. 3, pp. 279-82, Jan 01 1986.
[49] H. Li et al., "Microwave-assisted synthesis of N,P-doped carbon dots for fluorescent cell imaging," Microchimica Acta, vol. 183, no. 2, pp. 821-6, Feb 01 2016.
[50] H. Li et al., "One-step ultrasonic synthesis of water-soluble carbon nanoparticles with excellent photoluminescent properties," Carbon, vol. 49, no. 2, pp. 605-9, Feb 01 2011.
[51] N. Duran, M. B. Simoes, A. C. M. de Moraes, W. J. Favaro, and A. B. Seabra, "Nanobiotechnology of Carbon Dots: A Review," J Biomed Nanotechnol, vol. 12, no. 7, pp. 1323-47, Jul 2016.
[52] W. Wei, C. Xu, L. Wu, J. Wang, J. Ren, and X. Qu, "Non-enzymatic-browning-reaction: a versatile route for production of nitrogen-doped carbon dots with tunable multicolor luminescent display," Sci Rep, vol. 4, pp. 3564-70, Jan 6 2014.
[53] M. Jouyandeh et al., "Quantum dots for photocatalysis: synthesis and environmental applications," Green Chemistry, 10.1039/D1GC00639H vol. 23, no. 14, pp. 4931-54, May 25 2021.
[54] S. Hu, Z. Wei, Q. Chang, A. Trinchi, and J. Yang, "A facile and green method towards coal-based fluorescent carbon dots with photocatalytic activity," Applied Surface Science, vol. 378, pp. 402-7, Aug 15 2016.
[55] Q. Chang, K. K. Li, S. L. Hu, Y. G. Dong, and J. L. Yang, "Hydroxyapatite supported N-doped carbon quantum dots for visible-light photocatalysis," Materials Letters, vol. 175, pp.44-47,Mar 01 2016.
[56] K. Jiang, S. Sun, L. Zhang, Y. Wang, C. Cai, and H. Lin, "Bright-Yellow-Emissive N-Doped Carbon Dots: Preparation, Cellular Imaging, and Bifunctional Sensing," ACS Appl Mater Interfaces, vol. 7, no. 41, pp. 23231-8, Oct 21 2015.
[57] X. Lv, X. Wang, D. Huang, C. Niu, G. Zeng, and Q. Niu, "Quantum dots and p-phenylenediamine based method for the sensitive determination of glucose," Talanta, vol. 129, pp. 20-5, Nov 2014.
[58] J. Feng, Y. Chen, Y. Han, J. Liu, C. Ren, and X. Chen, "Fluorescent carbon nanoparticles: A low-temperature trypsin-assisted preparation and Fe(3+) sensing," Anal Chim Acta, vol. 926, pp. 107-17, Jul 5 2016.
[59] J. Ge et al., "Red-Emissive Carbon Dots for Fluorescent, Photoacoustic, and Thermal Theranostics in Living Mice," Adv Mater, vol. 27, no. 28, pp. 4169-77, Jul 22 2015.
[60] J. Wang, P. Zhang, C. Huang, G. Liu, K. C. Leung, and Y. X. Wang, "High Performance Photoluminescent Carbon Dots for In Vitro and In Vivo Bioimaging: Effect of Nitrogen Doping Ratios," Langmuir, vol. 31, no. 29, pp. 8063-73, Jul 28 2015.
[61] D. Wang et al., "Facile and Scalable Preparation of Fluorescent Carbon Dots for Multifunctional Applications," Engineering, vol. 3, no. 3, pp. 402-8, Jun 01 2017.
[62] K. Dehvari, K. Y. Liu, P.-J. Tseng, G. Gedda, W. M. Girma, and J.-Y. Chang, "Sonochemical-assisted green synthesis of nitrogen-doped carbon dots from crab shell as targeted nanoprobes for cell imaging," Journal of the Taiwan Institute of Chemical Engineers, vol. 95, pp. 495-503, Feb 01 2019.
[63] C. Ding, A. Zhu, and Y. Tian, "Functional surface engineering of C-dots for fluorescent biosensing and in vivo bioimaging," Acc Chem Res, vol. 47, no. 1, pp. 20-30, Jan 21 2014.
[64] H. Wang et al., "Biocompatible PEG-Chitosan@Carbon Dots Hybrid Nanogels for Two-Photon Fluorescence Imaging, Near-Infrared Light/pH Dual-Responsive Drug Carrier, and Synergistic Therapy," Advanced Functional Materials, vol. 25, no. 34, pp. 5537-47, Sep 01 2015.
[65] C. Tan, X. Su, C. Zhou, B. Wang, Q. Zhan, and S. He, "Acid-assisted hydrothermal synthesis of red fluorescent carbon dots for sensitive detection of Fe(iii)," RSC Advances, 10.1039/C7RA06223K vol. 7, no. 65, pp. 40952-6, Aug 22 2017.
[66] W. Song et al., "Ratiometric Detection of Intracellular Lysine and pH with One-Pot Synthesized Dual Emissive Carbon Dots," Anal Chem, vol. 89, no. 24, pp. 13626-13633, Dec 19 2017.
[67] J. Liu, D. Li, K. Zhang, M. Yang, H. Sun, and B. Yang, "One-Step Hydrothermal Synthesis of Nitrogen-Doped Conjugated Carbonized Polymer Dots with 31% Efficient Red Emission for In Vivo Imaging," Small, vol. 14, no. 15, pp. 1703919-28, Apr 01 2018.
[68] C. Tan et al., "Sulfuric Acid Assisted Preparation of Red-Emitting Carbonized Polymer Dots and the Application of Bio-Imaging," Nanoscale Res Lett, vol. 13, no. 1, pp. 272-7, Sep 10 2018.
[69] T. Shao, G. Wang, X. An, S. Zhuo, Y. Xia, and C. Zhu, "A reformative oxidation strategy using high concentration nitric acid for enhancing the emission performance of graphene quantum dots," RSC Advances, 10.1039/C4RA06935H vol. 4, no. 89, pp. 47977-81, Sep 10 2014.
[70] J. Tang et al., "Influence of Group Modification at the Edges of Carbon Quantum Dots on Fluorescent Emission," Nanoscale Res Lett, vol. 14, no. 1, pp. 241-50, Sep 2 2019.
[71] M. Lan et al., "Two-photon-excited near-infrared emissive carbon dots as multifunctional agents for fluorescence imaging and photothermal therapy," Nano Research, vol. 10, no. 9, pp. 3113-23, Sep 01 2017.
[72] X. Bao et al., "In vivo theranostics with near-infrared-emitting carbon dots-highly efficient photothermal therapy based on passive targeting after intravenous administration," Light Sci Appl, vol. 7, pp. 91-101, 2018.
[73] M. Li et al., "Solvothermal conversion of coal into nitrogen-doped carbon dots with singlet oxygen generation and high quantum yield," Chemical Engineering Journal, vol. 320, pp. 570-5, Jul 15 2017.
[74] S. Wu, R. Zhou, H. Chen, J. Zhang, and P. Wu, "Highly efficient oxygen photosensitization of carbon dots: the role of nitrogen doping," Nanoscale, vol. 12, no. 9, pp. 5543-53, Mar 5 2020.
[75] Y. Li et al., "Nitrogen and sulfur co-doped carbon dots synthesis via one step hydrothermal carbonization of green alga and their multifunctional applications," Microchemical Journal, vol. 147, pp. 1038-47, Jun 01 2019.
[76] H. Wang et al., "Carbon Dots Derived from Citric Acid and Glutathione as a Highly Efficient Intracellular Reactive Oxygen Species Scavenger for Alleviating the Lipopolysaccharide-Induced Inflammation in Macrophages," ACS Appl Mater Interfaces, vol. 12, no. 37, pp. 41088-95, Sep 16 2020.
[77] J. Zhou et al., "Carbon dots doped with heteroatoms for fluorescent bioimaging: a review," Microchimica Acta, vol. 184, no. 2, pp. 343-68, Feb 01 2017.
[78] F. Li, D. Yang, and H. Xu, "Non-Metal-Heteroatom-Doped Carbon Dots: Synthesis and Properties," Chemistry, vol. 25, no. 5, pp. 1165-76, Jan 24 2019.
[79] A. Nasrin, M. Hassan, and V. G. Gomes, "Two-photon active nucleus-targeting carbon dots: enhanced ROS generation and photodynamic therapy for oral cancer," Nanoscale, vol. 12, no. 40, pp. 20598-603, Oct 22 2020.
[80] J. Zhao, F. Li, S. Zhang, Y. An, and S. Sun, "Preparation of N-doped yellow carbon dots and N, P co-doped red carbon dots for bioimaging and photodynamic therapy of tumors," New Journal of Chemistry, 10.1039/C8NJ06351F vol. 43, no. 16, pp. 6332-42, Mar 22 2019.
[81] Y. Sun, C. Shen, J. Wang, and Y. Lu, "Facile synthesis of biocompatible N, S-doped carbon dots for cell imaging and ion detecting," RSC Advances, 10.1039/C4RA13820A vol. 5, no. 21, pp. 16368-75, Jan 232015.
[82] S. Zhao et al., "Polythiophene-Based Carbon Dots for Imaging-Guided Photodynamic Therapy," ACS Applied Nano Materials, vol. 4, no. 10, pp. 10528-33, Oct 22 2021.
[83] J. Ge et al., "A graphene quantum dot photodynamic therapy agent with high singlet oxygen generation," Nat Commun, vol. 5, pp. 4596-603, Aug 8 2014.
[84] J. Ge et al., "Carbon Dots with Intrinsic Theranostic Properties for Bioimaging, Red-Light-Triggered Photodynamic/Photothermal Simultaneous Therapy In Vitro and In Vivo," Adv Healthc Mater, vol. 5, no. 6, pp. 665-75, Mar 23 2016.
[85] Y. Dong et al., "Carbon-based dots co-doped with nitrogen and sulfur for high quantum yield and excitation-independent emission," Angew Chem Int Ed Engl, vol. 52, no. 30, pp. 7800-4, Jul 22 2013.
[86] H. Ding, S. B. Yu, J. S. Wei, and H. M. Xiong, "Full-Color Light-Emitting Carbon Dots with a Surface-State-Controlled Luminescence Mechanism," ACS Nano, vol. 10, no. 1, pp. 484-91, Jan 26 2016.
[87] L. Song, Y. Cui, C. Zhang, Z. Hu, and X. Liu, "Microwave-assisted facile synthesis of yellow fluorescent carbon dots from o-phenylenediamine for cell imaging and sensitive detection of Fe3+ and H2O2," RSC Advances, 10.1039/C6RA02554D vol. 6, no. 21, pp. 17704-12,Feb 03 2016.
[88] T. Zhang et al., "A novel mechanism for red emission carbon dots: hydrogen bond dominated molecular states emission," Nanoscale, vol. 9, no. 35, pp. 13042-51, Sep 14 2017.
[89] H. Wang et al., "Excitation wavelength independent visible color emission of carbon dots," Nanoscale, vol. 9, no. 5, pp. 1909-15, Feb 2 2017.
[90] S. Civiš et al., "Formation of Methane and (Per)Chlorates on Mars," ACS Earth and Space Chemistry, vol. 3, no. 2, pp. 221-32, Feb 21 2019.
[91] M. Favaro et al., "Multiple doping of graphene oxide foams and quantum dots: new switchable systems for oxygen reduction and water remediation," Journal of Materials Chemistry A, 10.1039/C5TA01561H vol. 3, no. 27, pp. 14334-47, Jun 01 2015.
[92] S. Li, Y. Li, J. Cao, J. Zhu, L. Fan, and X. Li, "Sulfur-doped graphene quantum dots as a novel fluorescent probe for highly selective and sensitive detection of Fe(3+)," Anal Chem, vol. 86, no. 20, pp. 10201-7, Oct 21 2014.
[93] R. Konaka, E. Kasahara, W. C. Dunlap, Y. Yamamoto, K. C. Chien, and M. Inoue, "Irradiation of titanium dioxide generates both singlet oxygen and superoxide anion," Free Radical Biology and Medicine, vol. 27, no. 3, pp. 294-300, Aug 01 1999.
[94] Y. Noda, K. Anzai, A. Mori, M. Kohno, M. Shinmei, and L. Packer, "Hydroxyl and superoxide anion radical scavenging activities of natural source antioxidants using the computerized JES-FR30 ESR spectrometer system," Biochem Mol Biol Int, vol. 42, no. 1, pp. 35-44, Jan 17 1997.
[95] Y. Qiu et al., "Antioxidant chemistry of graphene-based materials and its role in oxidation protection technology," Nanoscale, vol. 6, no. 20, pp. 11744-55, Oct 21 2014.
[96] V. Ruiz, L. Yate, I. García, G. Cabanero, and H.-J. Grande, "Tuning the antioxidant activity of graphene quantum dots: Protective nanomaterials against dye decoloration," Carbon, vol. 116, pp. 366-74, May 01 2017.
[97] Y. Wang et al., "Optimizing oxygen functional groups in graphene quantum dots for improved antioxidant mechanism," Phys Chem Chem Phys, vol. 21, no. 3, pp. 1336-43, Jan 21 2019.

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