研究生: |
劉憓陵 Huey-ling Liu |
---|---|
論文名稱: |
PGA/PVA混摻薄膜接枝左旋維他命C探討 Investigation of PGA/PVA blend membrane grafted with L-vitamin C |
指導教授: |
楊銘乾
Ming-Chien Yang |
口試委員: |
蘇清淵
Ching-Iuan Su 于大光 none |
學位類別: |
碩士 Master |
系所名稱: |
工程學院 - 材料科學與工程系 Department of Materials Science and Engineering |
論文出版年: | 2006 |
畢業學年度: | 94 |
語文別: | 中文 |
論文頁數: | 46 |
中文關鍵詞: | 聚麩胺酸 、聚胜肽 、聚乙烯醇 、戊二醛 、左旋維他命C |
外文關鍵詞: | PGA, polypeptides, PVA, glutaraldehyde, Ascorbic |
相關次數: | 點閱:272 下載:0 |
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Na+-γ-poly(glutamic acid) (PGA)為一具有奇佳的高吸水性、生物可分解性、保濕性、無毒性等優良特性之高分子聚合物,因此用來與聚乙烯醇
(PVA)混摻製成薄膜。兩種高分子在室溫下且不需任何化學藥劑的條件下,PGA和PVA即可混合形成水膠。依不同比例之PGA/PVA (0%、10%、11.1%、12.5%、20%、27.3%、30%、40%、50%) 混摻薄膜測試在生理食鹽水中之膨潤度,證實其具有高吸濕性,之後以戊二醛與左旋維他命C共價結合,運用左旋維他命C之抗氧化能力,期能增加PGA/PVA混摻薄膜在生醫材料及化妝保養品產業上的應用。
Na+-γ-poly(glutamic acid) (PGA), a highly water-soluble, biodegradable, hygroscopic and non-cytotoxic polypeptides, was
chosen to fabricate the PGA/polyvinyl alcohol (PVA) blending membranes. By mixing PGA and PVA together, a hydrogel would
be formed at room temperature without any chemical treatment.It was proven to be a highly hygroscopic by mixing at different ratio
of PGA/PVA (0~50%) blending membranes for testing its swelling
ratio in normal saline. By glutaraldehyde to covalently bond L(+)-Ascorbic acid with PGA/PVA, the application of PGA/PVA
blending membranes can be broadened in medical devices and
cosmetic industries.
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